Bifidobacterium mechanisms of immune modulation and tolerance

SJ Gavzy, A Kensiski, ZL Lee, EF Mongodin, B Ma… - Gut …, 2023 - Taylor & Francis
Bifidobacterium is a widely distributed commensal bacterial genus that displays beneficial
pro-homeostatic and anti-inflammatory immunomodulatory properties. Depletion or absence …

[HTML][HTML] Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating …

J Wang, X Guo, Z Zou, M Yu, X Li, H Xu, Y Chen… - Biomedicine & …, 2023 - Elsevier
Renal interstitial fibrosis (RIF), a progressive process affecting the kidneys in chronic kidney
disease (CKD), currently lacks an effective therapeutic intervention. Traditional Chinese …

The Gut Microbiome and Symptom Burden After Kidney Transplantation: An Overview and Research Opportunities

MB Lockwood, C Sung, SA Alvernaz… - Biological Research …, 2024 - journals.sagepub.com
Many kidney transplant recipients continue to experience high symptom burden despite
restoration of kidney function. High symptom burden is a significant driver of quality of life. In …

Mouse intestinal microbiome modulation by oral administration of a GABA-producing Bifidobacterium adolescentis strain

H Tamés, C Sabater, F Royo, A Margolles… - Microbiology …, 2024 - Am Soc Microbiol
Emerging evidence suggests that gut microbes can significantly contribute to central
nervous system (CNS) well functioning through several gut microbiome-brain signaling …

Rapid intestinal and systemic metabolic reprogramming in an immunosuppressed environment

B Ma, SJ Gavzy, M France, Y Song, HW Lwin… - BMC microbiology, 2023 - Springer
Intrinsic metabolism shapes the immune environment associated with immune suppression
and tolerance in settings such as organ transplantation and cancer. However, little is known …

[HTML][HTML] Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+ CD8αα+ intraepithelial T cells

N Rodriguez-Marino, CJ Royer… - Mucosal …, 2024 - Elsevier
The impact of dietary fiber on intestinal T cell development is poorly understood. Here we
show that a low fiber diet reduces MHC-II antigen presentation by small intestinal epithelial …

Prescription opioids induced microbial dysbiosis worsens severity of chronic pancreatitis and drives pain hypersensitivity

K Kesh, J Tao, N Ghosh, R Jalodia, S Singh… - Gut …, 2024 - Taylor & Francis
Opioids, such as morphine and oxycodone, are widely used for pain management
associated with chronic pancreatitis (CP); however, their impact on the progression and pain …

Establishing human microbial observatory programs in low‐and middle‐income countries

JI Gordon, MJ Barratt, MC Hibberd… - Annals of the New …, 2024 - Wiley Online Library
Studies of the human microbiome are progressing rapidly but have largely focused on
populations living in high‐income countries. With increasing evidence that the microbiome …

PUPpy: a primer design pipeline for substrain-level microbial detection and absolute quantification

H Ghezzi, YM Fan, KM Ng, JC Burckhardt, DM Pepin… - Msphere, 2024 - journals.asm.org
Characterizing microbial communities at high resolution and with absolute quantification is
crucial to unravel the complexity and diversity of microbial ecosystems. This can be …

[HTML][HTML] An in-depth investigation of the microbiota and its virulence factors associated with severe udder cleft dermatitis lesions

AS Vermeersch, M Ali, Y Gansemans… - Journal of Dairy …, 2024 - Elsevier
Udder cleft dermatitis (UCD) is a skin condition affecting the anterior parts of the udder in
dairy cattle. In the present study, we aimed to shed light on the microbiota in severe UCD …