The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI

C Dawes, AML Pedersen, A Villa, J Ekström… - Archives of oral …, 2015 - Elsevier
This narrative review of the functions of saliva was conducted in the PubMed, Embase and
Web of Science databases. Additional references relevant to the topic were used, as our key …

Genetic background of taste perception, taste preferences, and its nutritional implications: a systematic review

J Diószegi, E Llanaj, R Ádány - Frontiers in genetics, 2019 - frontiersin.org
Background: The rise in nutrition-related morbidity and mortality requires public health
intervention programs targeting nutritional behavior. In addition to socio-economical, socio …

The bad taste of medicines: overview of basic research on bitter taste

JA Mennella, AC Spector, DR Reed, SE Coldwell - Clinical therapeutics, 2013 - Elsevier
Background Many active pharmaceutical ingredients taste bitter and thus are aversive to
children as well as many adults. Encapsulation of the medicine in pill or tablet form, an …

Mechanisms of astringency: Structural alteration of the oral mucosal pellicle by dietary tannins and protective effect of bPRPs

S Ployon, M Morzel, C Belloir, A Bonnotte, E Bourillot… - Food chemistry, 2018 - Elsevier
The interaction of tannins with salivary proteins is involved in astringency. This paper
focussed on saliva lining oral mucosae, the mucosal pellicle. Using a cell-based model, the …

Saliva and the control of its secretion

J Ekström, N Khosravani, M Castagnola… - … : Diagnosis and treatment, 2019 - Springer
The various functions of saliva—among them digestive, protective, and trophic ones—not
just limited to the mouth and the relative contribution of the different types of gland to the total …

Taste Perception of Sweet, Sour, Salty, Bitter, and Umami and Changes Due to l-Arginine Supplementation, as a Function of Genetic Ability to Taste 6-n …

M Melis, I Tomassini Barbarossa - Nutrients, 2017 - mdpi.com
Behavioral reaction to different taste qualities affects nutritional status and health. 6-n-
Propylthiouracil (PROP) tasting has been reported to be a marker of variation in taste …

Genetic Sensitivity to the Bitter Taste of 6-n-Propylthiouracil (PROP) and Its Association with Physiological Mechanisms Controlling Body Mass Index (BMI)

BJ Tepper, S Banni, M Melis, R Crnjar… - Nutrients, 2014 - mdpi.com
Taste sensitivity to the bitter compound 6-n-propylthiouracil (PROP) is considered a marker
for individual differences in taste perception that may influence food preferences and eating …

Molecular mechanisms of taste recognition: considerations about the role of saliva

TK Fábián, A Beck, P Fejérdy, P Hermann… - International Journal of …, 2015 - mdpi.com
The gustatory system plays a critical role in determining food preferences and food intake, in
addition to nutritive, energy and electrolyte balance. Fine tuning of the gustatory system is …

The functional and neurobiological properties of bad taste

LA Schier, AC Spector - Physiological reviews, 2019 - journals.physiology.org
The gustatory system serves as a critical line of defense against ingesting harmful
substances. Technological advances have fostered the characterization of peripheral …

The gustin (CA6) gene polymorphism, rs2274333 (A/G), as a mechanistic link between PROP tasting and fungiform taste papilla density and maintenance

M Melis, E Atzori, S Cabras, A Zonza, C Calò, P Muroni… - PloS one, 2013 - journals.plos.org
Taste sensitivity to PROP varies greatly among individuals and is associated with
polymorphisms in the bitter receptor gene TAS2R38, and with differences in fungiform …