[HTML][HTML] The role of intolerance of uncertainty in classical threat conditioning: Recent developments and directions for future research
Intolerance of uncertainty (IU), the tendency to find uncertainty aversive, is an important
transdiagnostic dimension in mental health disorders. Over the last decade, there has been …
transdiagnostic dimension in mental health disorders. Over the last decade, there has been …
Measuring learning in human classical threat conditioning: Translational, cognitive and methodological considerations
Threat conditioning is a laboratory model of associative learning across species that is often
used in research on the etiology and treatment of anxiety disorders. At least 10 different …
used in research on the etiology and treatment of anxiety disorders. At least 10 different …
Anxiety and the neurobiology of temporally uncertain threat anticipation
J Hur, JF Smith, KA DeYoung… - Journal of …, 2020 - Soc Neuroscience
When extreme, anxiety—a state of distress and arousal prototypically evoked by uncertain
danger—can be debilitating. Uncertain anticipation is a shared feature of situations that elicit …
danger—can be debilitating. Uncertain anticipation is a shared feature of situations that elicit …
Bed nucleus of the stria terminalis regulates fear to unpredictable threat signals
The bed nucleus of the stria terminalis (BNST) has been implicated in conditioned fear and
anxiety, but the specific factors that engage the BNST in defensive behaviors are unclear …
anxiety, but the specific factors that engage the BNST in defensive behaviors are unclear …
[HTML][HTML] Responding to uncertain threat: A potential mediator for the effect of mindfulness on anxiety
I Papenfuss, MJJ Lommen, C Grillon… - Journal of Anxiety …, 2021 - Elsevier
Mindfulness-based interventions have gained extensive support for their application in the
treatment of anxiety. However, their mechanisms remain largely unexplored. Excessive …
treatment of anxiety. However, their mechanisms remain largely unexplored. Excessive …
Intolerance of uncertainty is associated with heightened responding in the prefrontal cortex during cue-signalled uncertainty of threat
Heightened responding to uncertain threat is considered a hallmark of anxiety disorder
pathology. We sought to determine whether individual differences in self-reported …
pathology. We sought to determine whether individual differences in self-reported …
An experimental investigation into the mediating role of pain-related fear in boosting nocebo hyperalgesia
MA Thomaidou, DS Veldhuijzen, A Meulders… - Pain, 2021 - journals.lww.com
Nocebo hyperalgesia refers to increases in perceived pain that putatively result from
negative expectations regarding a nocebo stimulus (eg, an inert treatment, compared with …
negative expectations regarding a nocebo stimulus (eg, an inert treatment, compared with …
Uncertain in the face of change: Lack of contingency shift awareness during extinction is associated with higher fear-potentiated startle and PTSD symptoms in …
Intolerance of uncertainty is a transdiagnostic risk factor for fear-related disorders and is
associated with higher levels of anxiety in children and adolescents. It is unclear how …
associated with higher levels of anxiety in children and adolescents. It is unclear how …
What do I do now? Intolerance of uncertainty is associated with discrete patterns of anticipatory physiological responding to different contexts
J Morriss - Psychophysiology, 2019 - Wiley Online Library
Heightened physiological responses to uncertainty are a common hallmark of anxiety
disorders. Many separate studies have examined the relationship between individual …
disorders. Many separate studies have examined the relationship between individual …
Dissociable impact of childhood trauma and deployment trauma on affective modulation of startle
Trauma disorders are often associated with alterations in aversive anticipation and
disruptions in emotion/fear circuits. Heightened or blunted anticipatory responding to …
disruptions in emotion/fear circuits. Heightened or blunted anticipatory responding to …