Glioblastoma microenvironment—from biology to therapy
Glioblastoma (GBM) is the most aggressive primary brain cancer. These tumors exhibit high
intertumoral and intratumoral heterogeneity in neoplastic and nonneoplastic compartments …
intertumoral and intratumoral heterogeneity in neoplastic and nonneoplastic compartments …
Pro-vs. anti-inflammatory features of monocyte subsets in glioma patients
N Lehman, W Kowalska, M Zarobkiewicz… - International Journal of …, 2023 - mdpi.com
Monocytes constitute a heterogenous group of antigen-presenting cells that can be
subdivided based on CD14, CD16 and SLAN expression. This division reflects the …
subdivided based on CD14, CD16 and SLAN expression. This division reflects the …
Integrated analysis of genome-wide DNA methylation and cancer-associated fibroblasts identified prognostic biomarkers and immune checkpoint blockade in lower …
J Dong, F Wang, X Gao, H Zhao, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Cancer-associated fibroblasts (CAFs) are vital components of prominent
cellular components in lower-grade gliomas (LGGs) that contribute to LGGs' progression …
cellular components in lower-grade gliomas (LGGs) that contribute to LGGs' progression …
A comprehensive meta-analysis of tissue resident memory T cells and their roles in shaping immune microenvironment and patient prognosis in non-small cell lung …
Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells
that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance …
that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance …
Integrating genomics and AI to uncover molecular targets for mRNA vaccine development in lupus nephritis
L Mou, Y Lu, Z Wu, Z Pu, M Wang - Frontiers in Immunology, 2024 - frontiersin.org
Lupus nephritis (LN), a complex complication of systemic lupus erythematosus, requires in-
depth cellular and molecular analysis for advanced treatment strategies, including mRNA …
depth cellular and molecular analysis for advanced treatment strategies, including mRNA …
Tissue-resident memory T cell signatures from single-cell analysis associated with better melanoma prognosis
Tissue-resident memory T cells (T RM) are a specialized T cell population residing in
peripheral tissues. The presence and potential impact of T RM in the tumor immune …
peripheral tissues. The presence and potential impact of T RM in the tumor immune …