Introduction Cartilage regeneration and restoration is a major topic in orthopedic research
as cartilaginous degeneration and damage is associated with osteoarthritis and joint …

The design and manufacture of artificial tissue for knee joints have been highlighted recently
among researchers which necessitates an apt approach for its assessment. Even though …

Recent advances in the development of new drugs to halt or even reverse the progression of
Osteoarthritis at an early‐stage requires new tools to detect early degeneration of articular …

Namely, in the last two decades, large animal models–small ruminants (sheep and goats),
pigs, dogs and horses–have been used to study the physiopathology and to develop new …

Cartilage defect is common in clinical but notoriously difficult to treat for low regenerative
and migratory capacity of chondrocytes. Biodegradable tissue engineering nano-scaffold …

Cartilage repair remains a major challenge and treatment of (osteo) chondral defects
generally results in poor quality fibrous repair tissue. Our approach aims to address some of …

Quantitative assessments of articular cartilage function are needed to aid clinical decision
making. Our objectives were to develop a new electromechanical grade to assess …

Purpose: Characterized cartilage lesions have a distinct impact on postoperative clinical
outcome, which is still being evaluated. The purpose of this study was to assess the …

Objective Reliable outcome measures are essential to predict the success of cartilage repair
techniques. Histology is probably the gold standard, but magnetic resonance imaging (MRI) …

Objective The objective of this study was to assess a novel 3D microstructured scaffold
seeded with allogeneic chondrocytes (cells) in a rabbit osteochondral defect model. Design …