Genetic and biochemical changes of the serotonergic system in migraine pathobiology

CF Gasparini, RA Smith, LR Griffiths - The journal of headache and pain, 2017 - Springer
Migraine is a brain disorder characterized by a piercing headache which affects one side of
the head, located mainly at the temples and in the area around the eye. Migraine imparts …

Maternal diet disrupts the placenta–brain axis in a sex-specific manner

AM Ceasrine, BA Devlin, JL Bolton, LA Green… - Nature …, 2022 - nature.com
High maternal weight is associated with detrimental outcomes in offspring, including
increased susceptibility to neurological disorders such as anxiety, depression and …

Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice

X Zhang, K Yoshihara, N Miyata, T Hata… - Physiology & …, 2022 - Elsevier
Important precursors of monoaminergic neurotransmitters, dietary tryptophan (TRP),
tyrosine, and phenylalanine (all referred to as TTP), play crucial roles in a wide range of …

Amino acid challenge and depletion techniques in human functional neuroimaging studies: an overview

CS Biskup, T Gaber, K Helmbold, S Bubenzer-Busch… - Amino acids, 2015 - Springer
Imbalances of neurotransmitter systems, particularly serotonin (5-HT) and dopamine (DA),
are known to play an essential role in many neuropsychiatric disorders. The transient …

Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway

L Wang, X Fan, J Han, M Cai, X Wang… - Frontiers in …, 2020 - frontiersin.org
The precipitous increase in occurrence of non-alcoholic steatohepatitis (NASH) is a serious
threat to public health worldwide. The pathogenesis of NASH has not yet been thoroughly …

Perinatal western‐type diet and associated gestational weight gain alter postpartum maternal mood

JL Bolton, MG Wiley, B Ryan, S Truong… - Brain and …, 2017 - Wiley Online Library
Introduction The role of perinatal diet in postpartum maternal mood disorders, including
depression and anxiety, remains unclear. We investigated whether perinatal consumption of …

Simplified dietary acute tryptophan depletion: effects of a novel amino acid mixture on the neurochemistry of C57BL/6J mice

CL Sánchez, AED Van Swearingen… - Food & nutrition …, 2015 - Taylor & Francis
Background Diet and nutrition can impact on the biological processes underpinning
neuropsychiatric disorders. Amino acid (AA) mixtures lacking a specific neurotransmitter …

Change in electrodermal activity after acute tryptophan depletion associated with aggression in young people with attention deficit hyperactivity disorder (ADHD)

GG Von Polier, CS Biskup, WF Kötting… - Journal of neural …, 2014 - Springer
We investigated the impact of acute tryptophan depletion (ATD) and reduced brain serotonin
synthesis on physiological arousal in 15 young people with ADHD participating in an …

The role of serotonin (5-HT) in behavioral control: findings from animal research and clinical implications

CL Sanchez, CS Biskup, S Herpertz… - International Journal …, 2015 - academic.oup.com
The neurotransmitters serotonin and dopamine both have a critical role in the underlying
neurobiology of different behaviors. With focus on the interplay between dopamine and …

Effects of dietary tryptophan and phenylalanine–tyrosine depletion on phasic alertness in healthy adults–a pilot study

P Hildebrand, W Königschulte, TJ Gaber… - Food & nutrition …, 2015 - Taylor & Francis
Background The synthesis of the neurotransmitters serotonin (5-HT) and dopamine (DA) in
the brain can be directly altered by dietary manipulation of their relevant precursor amino …