Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Background The involvement of epigenetic mechanisms in intergenerational transmission of
stress effects has been demonstrated in animals but not in humans. Methods Cytosine …

Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
Main Content Skip to Main Menu Advertisement Child and Adolescent Psychiatric Clinics of …

Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

The ability to measure human aging from molecular profiles has practical implications in
many fields, including disease prevention and treatment, forensics, and extension of life …

The early-life social environment can induce stable changes that influence
neurodevelopment and mental health. Research focused on early-life adversity revealed …

This Technical Report was retired November 2021. Advances in fields of inquiry as diverse
as neuroscience, molecular biology, genomics, developmental psychology, epidemiology …