In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …

Stem cells play an important role in restoring cardiac function in the damaged heart. In order
to mediate repair, stem cells need to replace injured tissue by differentiating into specialized …

This paper aims to provide an important update on the recent preclinical and clinical trials
using cell therapy strategies and engineered heart tissues for the treatment of postinfarction …

Objectives The clinical translation of cell-based therapies for ischemic heart disease has
been limited because of low cell retention (< 1%) within, and poor targeting to, ischemic …

Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial
homoeostasis and in the process of new vessel formation. Experimental and clinical studies …

Endothelial progenitor cells (EPC) play a fundamental role in tissue regeneration and
vascular repair. Current research suggests that EPC are more resistant to oxidative stress as …

Mild cognitive impairment is a well-documented consequence of whole brain radiation
therapy (WBRT) that affects 40-50% of long-term brain tumor survivors. The exact …

The role of the immune system is to recognize pathogens, tumor cells or dead cells and to
react with a very specific and localized response. By taking advantage of a highly …

Ischemic stroke continues to be a leading cause of mortality and morbidity in the world.
Despite recent advances in the field of stroke medicine, thrombolysis with recombinant …

Immunosuppressants are a mandatory therapy for transplant patients to avoid rejection of
the transplanted organ by the immune system. However, there are several known side …