Unlocking the potential of microfluidics in mass spectrometry-based immunopeptidomics for tumor antigen discovery

C Stutzmann, J Peng, Z Wu, C Savoie, I Sirois… - Cell Reports …, 2023 - cell.com
The identification of tumor-specific antigens (TSAs) is critical for developing effective cancer
immunotherapies. Mass spectrometry (MS)-based immunopeptidomics has emerged as a …

Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of …

CS Lutz, AZ Hasan, S Bolotin, NS Crowcroft… - BMC infectious …, 2023 - Springer
Background As countries move towards or achieve measles elimination status,
serosurveillance is an important public health tool. However, a major challenge of …

Portable sample processing for molecular assays: application to Zika virus diagnostics

T Narahari, J Dahmer, A Sklavounos, T Kim… - Lab on a Chip, 2022 - pubs.rsc.org
This paper introduces a digital microfluidic (DMF) platform for portable, automated, and
integrated Zika viral RNA extraction and amplification. The platform features reconfigurable …

Digital microfluidics with distance-based detection–a new approach for nucleic acid diagnostics

M Ho, N Sathishkumar, AA Sklavounos, J Sun, I Yang… - Lab on a Chip, 2024 - pubs.rsc.org
There is great enthusiasm for using loop-mediated isothermal amplification (LAMP) in point-
of-care nucleic acid amplification tests (POC NAATs), as an alternative to PCR. While …

Digital Microfluidics for Sample Preparation in Low‐Input Proteomics

MK Steinbach, J Leipert, T Matzanke… - Small Methods, 2024 - Wiley Online Library
Low‐input proteomics, also referred to as micro‐or nanoproteomics, has become
increasingly popular as it allows one to elucidate molecular processes in rare biological …

[HTML][HTML] An integrated digital microfluidic electrochemical impedimetric lipopolysaccharide sensor based on toll-like receptor-4 protein

RPS de Campos, D Aggarwal, NWC Chan… - … and Bioelectronics: X, 2024 - Elsevier
The spread of infectious diseases poses a global threat to human health and the economy.
Conventional laboratory-based pathogen detection analytical techniques are reliable, but …

Integration of paper-based analytical devices with digital microfluidics for colorimetric detection of creatinine

LG Velasco, DS Rocha, RPS de Campos, WKT Coltro - Analyst, 2024 - pubs.rsc.org
Digital microfluidics (DMF) is a platform that enables the automated manipulation of
individual droplets of sizes ranging from nanoliter to microliter and can be coupled with …

Integration of complementary split-ring resonators into digital microfluidics for manipulation and direct sensing of droplet composition

D Aggarwal, RPS de Campos, AB Jemere, AJ Bergren… - Lab on a Chip, 2024 - pubs.rsc.org
This paper demonstrates the integration of complementary split-ring resonators (CSSRs)
with digital microfluidics (DMF) sample manipulation for passive, on-chip radio-frequency …

Toward Analysis at the Point of Need: A Digital Microfluidic Approach to Processing Multi‐Source Sexual Assault Samples

M Elsayed, L Bodo, C Gaoiran, P Keuhnelian… - Advanced …, 2024 - Wiley Online Library
Forensic case samples collected in sexual assaults typically contain DNA from multiple
sources, which complicates short‐tandem repeat (STR) profiling. These samples are …

Prevalencia, complicaciones y pruebas diagnósticas por sensibilidad y especificidad del perfil TORCH en gestantes y recién nacidos

JJU Cedeño, YLS Arteaga, ADC Jalca… - Revista Científica de …, 2024 - soeici.org
Las anomalías congénitas ocurren durante la vida intrauterina y pueden detectarse durante
el embarazo, el parto o posteriormente. El diagnóstico prenatal de estas anomalías busca …