Polycyclic aromatic hydrocarbons (PAHs) are a class of chemicals of considerable
environmental significance. PAHs are chemical contaminants of fused carbon and hydrogen …

Polycyclic aromatic hydrocarbon (PAH) derivatives constitute a significant class of emerging
contaminants that have been ubiquitously detected in diverse environmental matrixes, with …

The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to
environmental stimuli. It was recognized historically for its role in toxicology but, in recent …

Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …

Adipose tissue inflammation mediates the association between excessive body fat
accumulation and several chronic inflammatory diseases. A high prevalence of obesity …

This article is a comprehensive review on developmental origins of health and disease
regarding various factors related to the origins of cardiovascular diseases from early life. It …

Toxicogenomics is proposed to be a useful tool in human health risk assessment. However,
a systematic comparison of traditional risk assessment approaches with those applying …

Recent studies have shown that crude oil exposure affects cardiac development in fish by
disrupting excitation-contraction (EC) coupling. We previously found that eggs of Atlantic …

Background—Tobacco smoke contains numerous agonists of the aryl hydrocarbon receptor
(AhR) pathway, and activation of the AhR pathway was shown to promote atherosclerosis in …

Aging is the most important risk factor for the development of major life-threatening diseases
such as cardiovascular disorders, cancer, and neurodegenerative disorders. The aging …