Amyotrophic lateral sclerosis: a clinical review
P Masrori, P Van Damme - European journal of neurology, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting primarily the
motor system, but in which extra‐motor manifestations are increasingly recognized. The loss …
motor system, but in which extra‐motor manifestations are increasingly recognized. The loss …
Unraveling molecular and genetic insights into neurodegenerative diseases: Advances in understanding Alzheimer's, Parkinson's, and Huntington's diseases and …
AV Ciurea, AG Mohan, RA Covache-Busuioc… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases are, according to recent studies, one of the main causes of
disability and death worldwide. Interest in molecular genetics has started to experience …
disability and death worldwide. Interest in molecular genetics has started to experience …
Genotype-associated cerebellar profiles in ALS: focal cerebellar pathology and cerebro-cerebellar connectivity alterations
Objective Cerebellar disease burden and cerebro-cerebellar connectivity alterations are
poorly characterised in amyotrophic lateral sclerosis (ALS) despite the likely contribution of …
poorly characterised in amyotrophic lateral sclerosis (ALS) despite the likely contribution of …
Cognitive and behavioural impairment in amyotrophic lateral sclerosis
N Pender, M Pinto-Grau… - Current Opinion in …, 2020 - journals.lww.com
Cognitive and behavioural impairment is an important feature of ALS, and reflects broad
network dysfunction of frontostriatal and frontotemporal systems. Cognition and behaviour …
network dysfunction of frontostriatal and frontotemporal systems. Cognition and behaviour …
Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features
P Bede, A Murad, O Hardiman - Journal of neurology, 2021 - Springer
The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …
academically important, but the practical demands of clinical neurology centre on the …
Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections
F Christidi, E Karavasilis, M Rentzos, G Velonakis… - Neurobiology of …, 2019 - Elsevier
Although hippocampal involvement in amyotrophic lateral sclerosis (ALS) has been
consistently highlighted by postmortem studies, memory impairment remains under …
consistently highlighted by postmortem studies, memory impairment remains under …
Biomarkers in amyotrophic lateral sclerosis: current status and future prospects
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …
development. Categorization based on clinical features alone can help us predict the …
RNA deregulation in amyotrophic lateral sclerosis: the noncoding perspective
P Laneve, P Tollis, E Caffarelli - International journal of molecular …, 2021 - mdpi.com
RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways
underpinning biological processes are affected by the events governing the RNA life cycle …
underpinning biological processes are affected by the events governing the RNA life cycle …
Extra-motor cerebral changes and manifestations in primary lateral sclerosis
E Finegan, SLH Shing, RH Chipika, KM Chang… - Brain imaging and …, 2021 - Springer
Primary lateral sclerosis (PLS) is classically considered a 'pure'upper motor neuron disorder.
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …
[HTML][HTML] Widespread subcortical grey matter degeneration in primary lateral sclerosis: a multimodal imaging study with genetic profiling
Background Primary lateral sclerosis (PLS) is a low incidence motor neuron disease which
carries a markedly better prognosis than amyotrophic lateral sclerosis (ALS). Despite …
carries a markedly better prognosis than amyotrophic lateral sclerosis (ALS). Despite …