Leaves provide energy for plants, and consequently for animals, through photosynthesis.
Despite their important functions, plant leaf developmental processes and their underlying …

Mutations of the retinoblastoma tumour suppressor gene (RB1) or components regulating
the RB pathway have been identified in almost every human malignancy. The E2F …

Developmental and environmental signals converge on cell cycle machinery to achieve
proper and flexible organogenesis under changing environments. Studies on the plant cell …

A great many cell types are necessary for the myriad capabilities of complex, multicellular
organisms. One interesting aspect of this diversity of cell type is that many cells in diploid …

In endoreplication cell cycles, known as endocycles, cells successively replicate their
genomes without segregating chromosomes during mitosis and thereby become polyploid …

Through its photosynthetic capacity the leaf provides the basis for growth of the whole plant.
In order to improve crops for higher productivity and resistance for future climate scenarios, it …

The leaf epidermis represents a multifunctional tissue consisting of trichomes, pavement
cells and stomata, the specialized cellular pores of the leaf. Pavement cells and stomata …

Genome integrity is continuously threatened by external stresses and endogenous hazards
such as DNA replication errors and reactive oxygen species. The DNA damage checkpoint …

Background E2F transcription factors are considered to be important drivers of tumour
growth. E2F7 is an atypical E2F factor, and its role in glioblastoma remains undefined …

Regeneration of a tissue damaged by injury represents a physiological response for organ
recovery 1–3. Although this regeneration process is conserved across multicellular taxa …