The role of microRNAs in myocardial infarction: from molecular mechanism to clinical application

T Sun, YH Dong, W Du, CY Shi, K Wang… - International journal of …, 2017 - mdpi.com
MicroRNAs (miRNAs) are a class of small single-stranded and highly conserved non-coding
RNAs, which are closely linked to cardiac disorders such as myocardial infarction (MI) …

Epigenetic biomarkers in cardiovascular diseases

C Soler-Botija, C Gálvez-Montón… - Frontiers in genetics, 2019 - frontiersin.org
Cardiovascular diseases are the number one cause of death worldwide and greatly impact
quality of life and medical costs. Enormous effort has been made in research to obtain new …

Use of circulating microRNAs to diagnose acute myocardial infarction

Y Devaux, M Vausort, E Goretti, PV Nazarov… - Clinical …, 2012 - academic.oup.com
BACKGROUND Rapid and correct diagnosis of acute myocardial infarction (MI) has an
important impact on patient treatment and prognosis. We compared the diagnostic …

[HTML][HTML] Human circulating microRNA-1 and microRNA-126 as potential novel indicators for acute myocardial infarction

G Long, F Wang, Q Duan, F Chen, S Yang… - … journal of biological …, 2012 - ncbi.nlm.nih.gov
Circulating miRNAs have been shown as promising biomarkers for various pathologic
conditions. The aim of this study was to clarify that circulating miR-1 and miR-126 in human …

[HTML][HTML] miRNA expression profiles in cerebrospinal fluid and blood of patients with acute ischemic stroke

SS Sørensen, AB Nygaard, MY Nielsen… - Translational stroke …, 2014 - Springer
The aims of the study were (1) to determine whether miRNAs (microRNAs) can be detected
in the cerebrospinal fluid (CSF) and blood of patients with ischemic stroke and (2) to …

Exercise training restores the cardiac microRNA-1 and −214 levels regulating Ca2+ handling after myocardial infarction

SFS Melo, VG Barauna, VJ Neves, T Fernandes… - BMC cardiovascular …, 2015 - Springer
Background Impaired cardiomyocyte contractility and calcium handling are hallmarks of left
ventricular contractile dysfunction. Exercise training has been used as a remarkable strategy …

Circulating miR-30a, miR-195 and let-7b associated with acute myocardial infarction

G Long, F Wang, Q Duan, S Yang, F Chen, W Gong… - PloS one, 2012 - journals.plos.org
Background MicroRNAs (miRNAs) play key roles in diverse biological and pathological
processes, including the regulation of proliferation, apoptosis, angiogenesis and cellular …

Circulatory miR-133b and miR-21 as novel biomarkers in early prediction and diagnosis of coronary artery disease

D Kumar, R Narang, V Sreenivas, V Rastogi, J Bhatia… - Genes, 2020 - mdpi.com
While coronary artery disease (CAD) has become a major threat worldwide, the timely
biomarker-based early diagnosis of CAD remains a major unmet clinical challenge. We …

Serum microRNAs profile from genome-wide serves as a fingerprint for diagnosis of acute myocardial infarction and angina pectoris

C Li, Z Fang, T Jiang, Q Zhang, C Liu, C Zhang… - BMC medical …, 2013 - Springer
Background In order to identify miRNAs expression profiling from genome-wide screen for
diagnosis of acute myocardial infarction (AMI) and angina pectoris (AP), we investigated the …

TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs

M Lu, B Shi, J Wang, Q Cao, Q Cui - BMC bioinformatics, 2010 - Springer
Background MicroRNAs (miRNAs) are a class of important gene regulators. The number of
identified miRNAs has been increasing dramatically in recent years. An emerging major …