Nervonic acid and its sphingolipids: Biological functions and potential food applications

NV Phung, F Rong, WY Xia, Y Fan, XY Li… - Critical reviews in …, 2024 - Taylor & Francis
Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …

Advances in lipidomics

HF Avela, H Siren - Clinica Chimica Acta, 2020 - Elsevier
The present article examines recently published literature on lipids, mainly focusing on
research involving glycero-, glycerophospho-and sphingo-lipids. The primary aim is …

Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations

J Rizo, L Sari, K Jaczynska… - Proceedings of the …, 2024 - National Acad Sciences
The SNAP receptor (SNARE) proteins syntaxin-1, SNAP-25, and synaptobrevin mediate
neurotransmitter release by forming tight SNARE complexes that fuse synaptic vesicles with …

Gut microbiota disturbance exaggerates battery wastewater-induced hepatotoxicity through a gut-liver axis

J Liao, Y Liu, J Yi, Y Li, Q Li, Y Li, P Shang… - Science of The Total …, 2022 - Elsevier
As the primary source of electricity for various devices, batteries are important contributors to
the overall electronic waste generated; and are widely considered a source of highly …

Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: a machine-learning approach

JM Urman, JM Herranz, I Uriarte, M Rullán, D Oyón… - Cancers, 2020 - mdpi.com
Cholangiocarcinoma (CCA) and pancreatic adenocarcinoma (PDAC) may lead to the
development of extrahepatic obstructive cholestasis. However, biliary stenoses can also be …

Machine learning of human plasma lipidomes for obesity estimation in a large population cohort

MJ Gerl, C Klose, MA Surma, C Fernandez… - PLoS …, 2019 - journals.plos.org
Obesity is associated with changes in the plasma lipids. Although simple lipid quantification
is routinely used, plasma lipids are rarely investigated at the level of individual molecules …

[HTML][HTML] Ceramide regulation of autophagy: A biophysical approach

YR Varela, MN Iriondo, FM Goñi, A Alonso… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Specific membrane lipids play unique roles in (macro) autophagy. Those include
phosphatidylethanolamine, to which LC3/GABARAP autophagy proteins become covalently …

Plant exosome-like nanovesicles derived from sesame leaves as carriers for luteolin delivery: Molecular docking, stability and bioactivity

D Jiang, Z Li, H Liu, H Liu, X Xia, X Xiang - Food Chemistry, 2024 - Elsevier
The growing recognition of luteolin (Lu) as a vital functional component is attributed to its
notable bioactive properties. However, the effective use of Lu is hindered by its inherent …

Metabolomics of Spleen-Yang deficiency syndrome and the therapeutic effect of Fuzi Lizhong pill on regulating endogenous metabolism

Z Zhang, S Yang, X Lin, Y Huang, X Wei, J Zhou… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Spleen-Yang deficiency (SYD) is one of the
primary causes of many digestive diseases, such as ulcerative colitis (UC), and irritable …

Reorientation of interfacial water molecules during melting of brain sphingomyelin is associated with the phase transition of its C24: 1 sphingomyelin lipids

P Maleš, J Munivrana, L Pašalić, B Pem… - Chemistry and physics of …, 2024 - Elsevier
Melting of brain sphingomyelin (bSM) manifests as a broad feature in the DSC curve that
encompasses the temperature range of 25–45° C, with two distinguished maxima …