Point-of-care testing (POCT) allows physicians to detect and diagnose diseases at or near
the patient site, faster than conventional lab-based testing. The importance of POCT is …

Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …

The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Sickle cell disease is caused by an alteration in a single DNA base, but its clinical
manifestations are influenced by other genes and behavioral and environmental factors …

Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin
gene that leads to the production of abnormal hemoglobin called hemoglobin S. The …

Blood is the most intensely studied human biofluid and is used as the main indicator of the
health status of an individual. Blood is a very complex fluid, containing a multiplicity of …

In the 100 years since sickle cell anemia (SCA) was first described in the medical literature,
studies of its molecular and pathophysiological basis have been at the vanguard of scientific …

Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by
chronic haemolytic anaemia, painful episodes of vaso-occlusion, progressive organ failure …

Sickle cell disease (SCD) is a common, life‐threatening genetic disorder that is best
managed when diagnosed early by newborn screening. However, SCD is most prevalent in …

Sickle cell disease can be life-threatening or chronically debilitating for both children and
adults. Worldwide, more than 300 000 children are born with sickle cell disease every year …