Triple-negative breast cancer (TNBC) remains the most challenging breast cancer subtype
to treat. To date, therapies directed to specific molecular targets have rarely achieved …

Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Triple-negative breast cancer (TNBC) is a heterogeneous disease with poor prognosis that
lacks targeted therapies, especially in patients with chemotherapy-resistant disease. Since …

Noninvasive detection of aberrant DNA methylation could provide invaluable biomarkers for
earlier detection of triple‐negative breast cancer (TNBC) which could help clinicians with …

A key step in the process of metastasis is the epithelial-to-mesenchymal transition (EMT).
We hypothesized that epigenetic mechanisms play a key role in EMT and to test this …

Background Basal-like constitutes an important molecular subtype of breast cancer
characterised by an aggressive behaviour and a limited therapy response. The outcome of …

Triple-negative breast cancer (TNBC) cells have not been usefully classified, and no
targeted therapeutic plans are currently available, resulting in a high recurrence rate and …

Epigenetic alterations are a common hallmark of human cancer. Single epigenetic markers
are starting to be incorporated into clinical practice; however, the translational use of these …

Human carcinoembryonic antigen (CEA) is the prototypic member of a family of highly
related cell surface glycoproteins that includes carcinoembryonic antigen‐related cell …

Breast cancer is the most common cancer and leading cause of cancer death among
women worldwide, encompassing a wide heterogeneity of subtypes with different clinical …