HER2/neu: mechanisms of dimerization/oligomerization
PJ Brennan, T Kumogai, A Berezov, R Murali… - Oncogene, 2000 - nature.com
Within a multi-celled organism, regulation and organization require that biological signals be
transmitted from one cell to another, across cell membranes. Such is the case with growth …
transmitted from one cell to another, across cell membranes. Such is the case with growth …
The epidermal growth factor family
G Carpenter, MI Wahl - Peptide growth factors and their receptors I, 1990 - Springer
During the purification of nerve growth factor from mouse submaxillary glands by
carboxymethyl cellulose chromatography, distinct biological activities were noticed when a …
carboxymethyl cellulose chromatography, distinct biological activities were noticed when a …
Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
C Aiken, J Konner, NR Landau, ME Lenburg, D Trono - Cell, 1994 - cell.com
CD4 is crucial for antigen-driven helper T cell signaling and is used as receptor by the
human immunodeficiency virus (HIV). The HIV early protein Nef causes a loss of CD4 from …
human immunodeficiency virus (HIV). The HIV early protein Nef causes a loss of CD4 from …
[图书][B] Chemical reagents for protein modification
RL Lundblad - 2004 - taylorfrancis.com
Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …
encyclopedic work describing the many approaches to the site-specific modification of …
Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine …
TW Gadella Jr, TM Jovin - The Journal of cell biology, 1995 - rupress.org
The aggregation states of the epidermal growth factor receptor (EGFR) on single A431
human epidermoid carcinoma cells were assessed with two new techniques for determining …
human epidermoid carcinoma cells were assessed with two new techniques for determining …
Mechanism for activation of mutated epidermal growth factor receptors in lung cancer
M Red Brewer, CH Yun, D Lai… - Proceedings of the …, 2013 - National Acad Sciences
The initiation of epidermal growth factor receptor (EGFR) kinase activity proceeds via an
asymmetric dimerization mechanism in which a “donor” tyrosine kinase domain (TKD) …
asymmetric dimerization mechanism in which a “donor” tyrosine kinase domain (TKD) …
[图书][B] Structure in protein chemistry
J Kyte - 2006 - books.google.com
The second edition of Structure in Protein Chemistry showcases the latest developments
and innovations in the field of protein structure analysis and prediction. The book begins by …
and innovations in the field of protein structure analysis and prediction. The book begins by …
Regulation of cyclooxygenase-2 pathway by HER2 receptor
R Vadlamudi, M Mandal, L Adam, G Steinbach… - Oncogene, 1999 - nature.com
Emerging lines of evidence suggest that in addition to growth factors, the process of
colorectal tumorigenesis may also be driven by the upregulation of the inducible form of …
colorectal tumorigenesis may also be driven by the upregulation of the inducible form of …
[图书][B] Chemistry of protein and nucleic acid cross-linking and conjugation
SS Wong, DM Jameson, SS Wong - 2012 - api.taylorfrancis.com
It has been 20 years since the publication of Chemistry of Protein Conjugation and Cross-
Linking. During this period, great advances have been made in the area of cross-linking of …
Linking. During this period, great advances have been made in the area of cross-linking of …
Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with 125I-EGF
H Björkelund, L Gedda, P Barta, M Malmqvist… - PLoS …, 2011 - journals.plos.org
The tyrosine kinase inhibitor gefitinib inhibits growth in some tumor types by targeting the
epidermal growth factor receptor (EGFR). Previous studies show that the affinity of the EGF …
epidermal growth factor receptor (EGFR). Previous studies show that the affinity of the EGF …