Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

Recurrence mechanisms of non-muscle-invasive bladder cancer—A clinical perspective

JYC Teoh, AM Kamat, PC Black, P Grivas… - Nature Reviews …, 2022 - nature.com
Non-muscle-invasive bladder cancer (NMIBC) is an early-stage cancer without invasion into
the detrusor muscle layer. Transurethral resection of bladder tumour (TURBT) is a diagnostic …

Bladder cancer, version 3.2020, NCCN clinical practice guidelines in oncology

TW Flaig, PE Spiess, N Agarwal, R Bangs… - Journal of the National …, 2020 - jnccn.org
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Bladder Cancer focuses on the clinical presentation and workup of suspected bladder …

Pathologist-level interpretable whole-slide cancer diagnosis with deep learning

Z Zhang, P Chen, M McGough, F Xing… - Nature Machine …, 2019 - nature.com
Diagnostic pathology is the foundation and gold standard for identifying carcinomas.
However, high inter-observer variability substantially affects productivity in routine pathology …

Long non‐coding RNA UCA 1 increases chemoresistance of bladder cancer cells by regulating Wnt signaling

Y Fan, B Shen, M Tan, X Mu, Y Qin, F Zhang… - The FEBS …, 2014 - Wiley Online Library
Chemotherapy is a reasonable alternative to cystectomy in patients with invasive and
advanced bladder cancer. However, bladder cancer cells often develop drug resistance to …

Pharmacogenomics: biomarker-directed therapy for bladder cancer

RT Jones, KM Felsenstein… - Urologic Clinics, 2016 - urologic.theclinics.com
It is estimated that 74,000 people in the United States and roughly 386,000 people globally
will be newly diagnosed with bladder cancer in 2015. 1, 2 Bladder cancer represents a …

Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6

Z Liu, W Wang, J Jiang, E Bao, D Xu, Y Zeng, L Tao… - PloS one, 2013 - journals.plos.org
Long non-coding RNAs (lncRNAs) play important roles in diverse biological processes, such
as transcriptional regulation, cell growth and tumorigenesis. However, little is known about …

Systemic, perioperative management of muscle-invasive bladder cancer and future horizons

SA Funt, JE Rosenberg - Nature reviews Clinical oncology, 2017 - nature.com
Many patients diagnosed with muscle-invasive bladder cancer (MIBC) will develop distant
metastatic disease. Over the past three decades, perioperative cisplatin-based …

Defining progression in nonmuscle invasive bladder cancer: it is time for a new, standard definition

D Lamm, R Persad, M Brausi, R Buckley, JA Witjes… - The Journal of …, 2014 - Elsevier
Purpose Despite being one of the most important clinical outcomes in nonmuscle invasive
bladder cancer, there is currently no standard definition of disease progression. Major …

Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer

H Hirata, K Ueno, V Shahryari, Y Tanaka… - PloS one, 2012 - journals.plos.org
Onco-miR-182-5p has been reported to be over-expressed in bladder cancer (BC) tissues
however a detailed functional analysis of miR-182-5p has not been carried out in BC …