Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19
JP Bridges, EK Vladar, H Huang, RJ Mason - Thorax, 2022 - thorax.bmj.com
COVID-19 has different clinical stages, and effective therapy depends on the location and
extent of the infection. The purpose of this review is to provide a background for …
extent of the infection. The purpose of this review is to provide a background for …
[HTML][HTML] Epidemiology and immune pathogenesis of viral sepsis
GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
Pathogenesis of COVID-19 from a cell biology perspective
RJ Mason - European Respiratory Journal, 2020 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) is a major health concern and can be devastating,
especially for the elderly. COVID-19 is the disease caused by the SARS-CoV-2 virus …
especially for the elderly. COVID-19 is the disease caused by the SARS-CoV-2 virus …
[HTML][HTML] SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …
Molecular pathology of emerging coronavirus infections
LE Gralinski, RS Baric - The Journal of pathology, 2015 - Wiley Online Library
Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild,
upper respiratory tract infections to severe and life‐threatening lower respiratory tract …
upper respiratory tract infections to severe and life‐threatening lower respiratory tract …
[HTML][HTML] Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
C Tindle, MK Fuller, A Fonseca, S Taheri… - Elife, 2021 - elifesciences.org
Background: SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage
in the lungs in the setting of an overzealous immune response whose origin remains …
in the lungs in the setting of an overzealous immune response whose origin remains …
[HTML][HTML] Post-COVID-19 pulmonary fibrosis
A Mohammadi, I Balan, S Yadav, WF Matos… - Cureus, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions
worldwide with a high mortality rate due to a lack of definitive treatment. Despite having a …
worldwide with a high mortality rate due to a lack of definitive treatment. Despite having a …
[HTML][HTML] Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip
Mechanical breathing motions have a fundamental function in lung development and
disease, but little is known about how they contribute to host innate immunity. Here we use a …
disease, but little is known about how they contribute to host innate immunity. Here we use a …
Thoughts on the alveolar phase of COVID-19
RJ Mason - American Journal of Physiology-Lung Cellular …, 2020 - journals.physiology.org
COVID-19 can be divided into three clinical stages, and one can speculate that these stages
correlate with where the infection resides. For the asymptomatic phase, the infection mostly …
correlate with where the infection resides. For the asymptomatic phase, the infection mostly …
[HTML][HTML] Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus
Bioprinting is a new technology, which arranges cells with high spatial resolution, but its
potential to create models for viral infection studies has not yet been fully realized. The …
potential to create models for viral infection studies has not yet been fully realized. The …