Spectrophotometric versus spectrofluorometric assessment in the study of the relationships between lipid peroxidation and metabolic dysregulation

A Ungurianu, O Șeremet, D Grădinaru… - Chemical Biology & …, 2019 - Wiley Online Library
Reactive oxygen species are crucial to normal cell function, but are also part of the
pathogenesis of multiple modern maladies. As such, sensitive, fast, and reliable methods of …

Sorghum halepense (L.) Pers rhizomes inhibitory potential against diabetes and free radicals

MAR Shah, RA Khan, M Ahmed - Clinical Phytoscience, 2021 - Springer
Background Owing to the side effects of synthetic medicine and less effectiveness against
different syndromes, the researchers have focused on phytotherapy to overcome these …

Amelioration of hyperglycaemia and modulation of antioxidant status by Alcea rosea seeds in alloxan-induced diabetic rats

PA Dar, F Ali, IA Sheikh, SA Ganie… - Pharmaceutical biology, 2017 - Taylor & Francis
Abstract Context: Alcea rosea L.(Malvaceae) has various medicinal uses including
anticancer, anti-inflammatory and analgesic properties. However, there is no report on its …

Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract

H Dab, A Chehidi, M Tlili, A Ben Saad, A Khabir… - Biomarkers, 2022 - Taylor & Francis
Context Disorders associated with diabetes and the beneficial effects of pomegranate peel
extract (PPE) were widely reported. However effect of diabetes and PPE on extracellular …

Evaluating the Antihyperalgesic Potential of Sildenafil–Metformin Combination and Its Impact on Biochemical Markers in Alloxan-Induced Diabetic Neuropathy in Rats

C Pușcașu, S Negreș, CE Zbârcea, A Ungurianu… - Pharmaceuticals, 2024 - mdpi.com
(1) Background: Globally, about 600 million people are afflicted with diabetes, and one of its
most prevalent complications is neuropathy, a debilitating condition. At the present time, the …

Anti-diabetic activity of Iphiona aucheri leaf extract

MAR Shah, RA Khan, M Ahmed - ||| Bangladesh Journal of …, 2020 - bdpsjournal.org
The methanolic extract of Iphiona aucheri leaves and its n-hexane, chloroform and aqueous
fractions were screened for phytochemicals, cytotoxic effects, total phenolic contents …

The Influence of Sildenafil–Metformin Combination on Hyperalgesia and Biochemical Markers in Diabetic Neuropathy in Mice

C Pușcașu, A Ungurianu, OC Șeremet, C Andrei… - Medicina, 2023 - mdpi.com
Background and objectives: Worldwide, approximately 500 million people suffer from
diabetes and at least 50% of these people develop neuropathy. Currently, therapeutic …

[PDF][PDF] Correlations in silico/in vitro/in vivo regarding determinating acute toxicity in non-clinical experimental trial, according to bioethic regulations inforced by the …

S Negreş, M Dinu, RV Ancuceanu, TO Olaru… - …, 2015 - farmaciajournal.com
A non-clinical experimental trial on laboratory animals was conducted in order to determine
the acute toxicity of 7 newly synthesized compounds (derivatives of beta phenyl-ethyl …

[PDF][PDF] Pharmacotoxicological screening on new derivatives of beta-phenylethylamine, potential agonists of beta3-adrenergic receptors

S Negreş, A Zanfirescu, FE Ionică… - Romanian journal of …, 2016 - academia.edu
Abstract Background and Aims: Beta3-adrenergic receptors (beta3-ARs) have been initially
characterized in 1989. Afterwards, their tissue distribution was established: white and brown …

New potential Beta-3 adrenergic agonists with Beta-phenylethylamine structure, synthesized for the treatment of dyslipidemia and obesity

S Negreș, C Chiriță, AL Arsene… - Adiposity …, 2017 - books.google.com
Beta-3 adrenergic receptors have important physiological implications, being expressed in
many places in the body, including brown adipose tissue. Of the effects studied in preclinical …