Epigenetics in precision nutrition

X Li, L Qi - Journal of Personalized Medicine, 2022 - mdpi.com
Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

Shared genetic etiology underlying Alzheimer's disease and type 2 diabetes

K Hao, AF Di Narzo, L Ho, W Luo, S Li, R Chen… - Molecular aspects of …, 2015 - Elsevier
Epidemiological evidence supports the observation that subjects with type 2 diabetes (T2D)
are at higher risk to develop Alzheimer's disease (AD). However, whether and how these …

The time is right for a new classification system for diabetes: rationale and implications of the β-cell–centric classification schema

SS Schwartz, S Epstein, BE Corkey, SFA Grant… - Diabetes …, 2016 - Am Diabetes Assoc
The current classification system presents challenges to the diagnosis and treatment of
patients with diabetes mellitus (DM), in part due to its conflicting and confounding definitions …

[HTML][HTML] MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications

F Olivieri, L Spazzafumo, M Bonafè, R Recchioni… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Innovative biomarkers are required to manage type 2 diabetic patients (T2DM). We focused
our study on miR-126-3p and miR-21-5p levels, as biomarkers of endothelial function and …

A maternal high-fat diet induces DNA methylation changes that contribute to glucose intolerance in offspring

Q Zhang, X Xiao, J Zheng, M Li, M Yu, F Ping… - Frontiers in …, 2019 - frontiersin.org
Scope: Overnutrition in utero is a critical contributor to the susceptibility of diabetes by
programming, although the exact mechanism is not clear. In this paper, we aimed to study …

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes

N Mononen, LP Lyytikäinen, I Seppälä, PP Mishra… - Scientific reports, 2019 - nature.com
We analyzed the associations between whole blood microRNA profiles and the indices of
glucose metabolism and impaired fasting glucose and examined whether the discovered …

DNA methylation and type 2 diabetes: novel biomarkers for risk assessment?

GA Raciti, A Desiderio, M Longo, A Leone… - International Journal of …, 2021 - mdpi.com
Diabetes is a severe threat to global health. Almost 500 million people live with diabetes
worldwide. Most of them have type 2 diabetes (T2D). T2D patients are at risk of developing …

The action of polyphenols in diabetes mellitus and Alzheimer's disease: a common agent for overlapping pathologies

AC Silveira, JP Dias, VM Santos… - Current …, 2019 - ingentaconnect.com
Diabetes Mellitus (DM) and Alzheimer's disease (AD) are two prevalent diseases in modern
societies, which are caused mainly by current lifestyle, aging and genetic alterations. It has …

Epigenetic mechanisms of endocrine-disrupting chemicals in obesity

IC Nettore, F Franchini, G Palatucci, PE Macchia… - Biomedicines, 2021 - mdpi.com
The incidence of obesity has dramatically increased over the last decades. Recently, there
has been a growing interest in the possible association between the pandemics of obesity …

Nutritional factors, DNA methylation, and risk of type 2 diabetes and obesity: perspectives and challenges

L Parrillo, R Spinelli, A Nicolò, M Longo… - International journal of …, 2019 - mdpi.com
A healthy diet improves life expectancy and helps to prevent common chronic diseases such
as type 2 diabetes (T2D) and obesity. The mechanisms driving these effects are not fully …