[HTML][HTML] Metastatic uveal melanoma: The final frontier

ES Rantala, MM Hernberg, S Piperno-Neumann… - Progress in Retinal and …, 2022 - Elsevier
Abstract Treatment of primary intraocular uveal melanoma has developed considerably, its
driver genes are largely unraveled, and the ways to assess its risk for metastases are very …

Future perspectives of uveal melanoma blood based biomarkers

AB Beasley, FK Chen, TW Isaacs, ES Gray - British Journal of Cancer, 2022 - nature.com
Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults.
Despite successful local treatment of the primary tumour, metastatic disease develops in up …

Update on uveal melanoma: Translational research from biology to clinical practice

MA Ortega, O Fraile-Martinez… - International …, 2020 - spandidos-publications.com
Uveal melanoma is the most common type of intraocular cancer with a low mean annual
incidence of 5-10 cases per million. Tumours are located in the choroid (90%), ciliary body …

In-phase and opposed-phase imaging: applications of chemical shift and magnetic susceptibility in the chest and abdomen

AS Shetty, AL Sipe, M Zulfiqar, R Tsai, DA Raptis… - Radiographics, 2019 - pubs.rsna.org
For the radiologist performing body MRI, chemical shift imaging is a unique tool available to
investigate the cellular composition of tissue. By leveraging the inherent difference in …

Targeting GNAQ/11 through PKC inhibition in uveal melanoma

CD Lietman, M McKean - Cancer Gene Therapy, 2022 - nature.com
Uveal melanoma is a rare malignancy affecting 5.1 patients/million per year with definitive
treatment options of enucleation or radiation therapy to the primary tumor. Unfortunately, no …

Locoregional therapies for the treatment of uveal melanoma hepatic metastases

CF Gonsalves, RD Adamo… - Seminars in …, 2020 - thieme-connect.com
Uveal melanoma is the most common primary intraocular malignant tumor in adults.
Approximately 50% of patients develop metastatic disease of which greater than 90% of …

Nivolumab plus ipilimumab in metastatic uveal melanoma: a real-life, retrospective cohort of 47 patients

H Salaün, L de Koning, M Saint-Ghislain… - …, 2022 - Taylor & Francis
ABSTRACT Although combined PD-1/CTLA-4 inhibition showed limited efficacy in single-
arm, phase II trials in metastatic uveal melanoma (mUM), such combination appears …

Risk-stratified systemic surveillance in uveal melanoma

JM Davanzo, EM Binkley, JF Bena… - British Journal of …, 2019 - bjo.bmj.com
Background/Aim Molecular prognostication provides clinically applicable prognostic
information for patients with uveal melanoma. Most ocular oncologists recommend intensive …

Application of multimodal and molecular imaging techniques in the detection of choroidal melanomas

X Li, L Wang, L Zhang, F Tang, X Wei - Frontiers in oncology, 2021 - frontiersin.org
Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset
of such tumors is insidious, such that affected patients often have no pain or obvious …

[HTML][HTML] Hepatic ultrasonography compared with computed tomography and magnetic resonance imaging at diagnosis of metastatic uveal melanoma

ES Rantala, E Peltola, H Helminen, M Hernberg… - American Journal of …, 2020 - Elsevier
Purpose To evaluate the consistency of hepatic ultrasonography (US) with staging
computed tomography (CT) and magnetic resonance imaging (MRI), to analyze why US was …