Physiology of penile erection and pathophysiology of erectile dysfunction

AC Leung, GJ Christ, A Melman - Atlas of Male Sexual Dysfunction, 2004 - Springer
Until recently, erectile dysfunction (ED) was treated by either sexual counseling or penile
prosthesis implantation. The advent of intracavernous and transurethral agents has …

Anatomy, physiology, and pathophysiology of erectile dysfunction

C Gratzke, J Angulo, K Chitaley, Y Dai… - The journal of sexual …, 2010 - academic.oup.com
Introduction Significant scientific advances during the past 3 decades have deepened our
understanding of the physiology and pathophysiology of penile erection. A critical evaluation …

Validation of the erection hardness score

JP Mulhall, I Goldstein, AG Bushmakin… - The journal of sexual …, 2007 - academic.oup.com
Introduction Erection hardness is a fundamental component of erectile function, and is a very
specific and easily monitored outcome. The Erection Hardness Score (EHS) is a single-item …

[HTML][HTML] Metabolic syndrome and urologic diseases

I Gorbachinsky, H Akpinar, DG Assimos - Reviews in urology, 2010 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) is a complex entity consisting of multiple interrelated factors
including insulin resistance, central adiposity, dyslipidemia, endothelial dysfunction and …

Is there a role of hypoxemia in penile fibrosis: a viewpoint presented to the Society for the Study of Impotence

RB Moreland - International journal of impotence research, 1998 - nature.com
During erection, oxygen tension changes in the corpus cavernosum penis from 25–40 mm
Hg in the flaccid state to 90–100 mm Hg in the erect state. 1 The relationship between …

Effects of castration and androgen replacement on erectile function in a rabbit model

AM Traish, K Park, V Dhir, NN Kim, RB Moreland… - …, 1999 - academic.oup.com
We investigated, in a rabbit model, the effects of castration and testosterone replacement on:
1) the hemodynamics of the corpus cavernosum; 2) α-1 adrenergic receptor protein …

Histological alterations in cavernous tissue after radical prostatectomy

F Iacono, R Giannella, P Somma, G Manno… - The Journal of …, 2005 - auajournals.org
Purpose: Radical prostatectomy often results in erectile dysfunction because of lesions to
the erectile nerves. In this study we evaluated histomorphological alterations in cavernous …

Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit

KM AZADZOI, T TARCAN, MB SIROKY… - The Journal of …, 1999 - auajournals.org
Purpose: The overall goal was to determine whether chronic ischemia and
hypercholesterolemia interfere with bladder function and structure. The roles of …

Pathophysiology of erectile dysfunction

IS De Tejada, J Angulo, S Cellek… - The journal of sexual …, 2005 - academic.oup.com
Introduction Multiple regulatory systems are involved in normal erectile function. Disruption
of psychological, neurological, hormonal, vascular, and cavernosal factors, individually, or in …

Physiological regulation of penile arteries and veins

D Prieto - International journal of impotence research, 2008 - nature.com
Recent experimental evidence suggests that arterial insufficiency precedes the structural
and functional changes in corpora cavernosa (CC) leading to organic erectile dysfunction …