Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

Plasmodium vivax is geographically the most widely distributed cause of malaria in people,
with up to 2· 5 billion people at risk and an estimated 80 million to 300 million clinical cases …

Background Current understanding of the spatial epidemiology and geographical
distribution of Plasmodium vivax is far less developed than that for P. falciparum …

The relative contribution of founder effects and natural selection to the observed distribution
of human blood groups has been debated since blood group frequencies were shown to …

Plasmodium vivax threatens almost 40% of the world's population, resulting in 132-391
million clinical infections each year. Most of these cases originate from South East Asia and …

Blood group variants are characteristic of population groups, and can show conspicuous
geographic patterns. Interest in the global prevalence of the Duffy blood group variants is …

Background A research priority for Plasmodium vivax malaria is to improve our
understanding of the spatial distribution of risk and its relationship with the burden of P. vivax …

Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …

Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …

Long considered a benign infection, Plasmodium vivax is now recognized as a cause of
severe and fatal malaria, despite its low parasite biomass, the increased deformability of …