Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Keeping an eye on circadian time in clinical research and medicine

EB Klerman, A Brager, MA Carskadon… - Clinical and …, 2022 - Wiley Online Library
Background Daily rhythms are observed in humans and almost all other organisms. Most of
these observed rhythms reflect both underlying endogenous circadian rhythms and evoked …

Clinical utility of EEG in diagnosing and monitoring epilepsy in adults

WO Tatum, G Rubboli, PW Kaplan, SM Mirsatari… - Clinical …, 2018 - Elsevier
Electroencephalography (EEG) remains an essential diagnostic tool for people with epilepsy
(PWE). The International Federation of Clinical Neurophysiology produces new guidelines …

Circadian rhythm and epilepsy

S Khan, L Nobili, R Khatami, T Loddenkemper… - The Lancet …, 2018 - thelancet.com
Advances in diagnostic technology, including chronic intracranial EEG recordings, have
confirmed the clinical observation of different temporal patterns of epileptic activity and …

Novel approaches for assessing circadian rhythmicity in humans: a review

DJ Dijk, JF Duffy - Journal of biological rhythms, 2020 - journals.sagepub.com
The temporal organization of molecular and physiological processes is driven by
environmental and behavioral cycles as well as by self-sustained molecular circadian …

Effects of circadian disruption on the cardiometabolic system

M Rüger, FAJL Scheer - Reviews in Endocrine and Metabolic Disorders, 2009 - Springer
The presence of day–night variations in cardiovascular and metabolic functioning is well
known. However, only recently it has been shown that cardiovascular and metabolic …

[HTML][HTML] Thalamic deep brain stimulation modulates cycles of seizure risk in epilepsy

NM Gregg, V Sladky, P Nejedly, F Mivalt, I Kim… - Scientific reports, 2021 - nature.com
Chronic brain recordings suggest that seizure risk is not uniform, but rather varies
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …

Circadian rhythm sleep-wake disorders

M Pavlova - Continuum: Lifelong Learning in Neurology, 2017 - journals.lww.com
Abstract Purpose of Review: The endogenous circadian rhythms are one of the cardinal
processes that control sleep. They are self-sustaining biological rhythms with a periodicity of …

[HTML][HTML] Epilepsy occurrence and circadian rhythm: a bibliometrics study and visualization analysis via CiteSpace

D Zhong, S Luo, L Zheng, Y Zhang, R Jin - Frontiers in neurology, 2020 - frontiersin.org
Objective: This study aimed to review the research status and to demonstrate the hot spots
and frontiers of epilepsy and circadian rhythm via CiteSpace. Method: We searched Web of …

Cues for seizure timing

VR Rao, MG Leguia, TK Tcheng, MO Baud - Epilepsia, 2021 - Wiley Online Library
The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …