Impaired autonomic nervous system-microbiome circuit in hypertension: a premise for hypertension therapy
Hypertension affects an estimated 103 million Americans, yet gaps in knowledge continue to
limit its successful management. Rapidly emerging evidence is linking gut dysbiosis to many …
limit its successful management. Rapidly emerging evidence is linking gut dysbiosis to many …
A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from l-arginine or nitrite?
S Gambaryan, D Tsikas - Amino acids, 2015 - Springer
Abstract The NO/sGC/cGMP/PKG system is one of the most powerful mechanisms
responsible for platelet inhibition. In numerous publications, expression of functional NO …
responsible for platelet inhibition. In numerous publications, expression of functional NO …
Hypertension associated with hyperlipidemia induced different microRNA expression profiles in plasma, platelets, and platelet-derived microvesicles; effects of …
Aim: The aim of this study was to analyze the expressed profiles of miRNAs in plasma,
platelets, and platelet-derived microvesicles (PMVs) obtained from experimental induced …
platelets, and platelet-derived microvesicles (PMVs) obtained from experimental induced …
[HTML][HTML] Circulating microparticles and endothelial progenitor cells in atherosclerosis: pharmacological effects of irbesartan
A Georgescu, N Alexandru, E Andrei, I Titorencu… - Journal of Thrombosis …, 2012 - Elsevier
Aims: This study aimed to (i) employ our newly designed model, the hypertensive–
hypercholesterolemic hamster (HH), in order to find out whether a correlation exists between …
hypercholesterolemic hamster (HH), in order to find out whether a correlation exists between …
Platelet dysfunction in vascular pathologies and how can it be treated
Cardiovascular diseases are one of the leading causes of morbidity and mortality in
industrialized countries, and although many processes play a role in the development of …
industrialized countries, and although many processes play a role in the development of …
Effects of transplanted circulating endothelial progenitor cells and platelet microparticles in atherosclerosis development
A Georgescu, N Alexandru, E Andrei… - Biology of the …, 2016 - Wiley Online Library
Background Information Atherosclerosis is an inflammatory disease, in which risk factors
such as hyperlipidemia and hypertension affect the arterial endothelium, resulting in …
such as hyperlipidemia and hypertension affect the arterial endothelium, resulting in …
Microarray truths and consequences
R Sasik, CH Woelk, J Corbeil - Journal of molecular …, 2004 - jme.bioscientifica.com
Dear Readers, Having served as Editor-in-Chief of Journal of Molecular Endocrinology for
seven years, I would like to take this opportunity to thank all those who have contributed to …
seven years, I would like to take this opportunity to thank all those who have contributed to …
Cilostazol exerts antiplatelet and anti‐inflammatory effects through AMPK activation and NF‐kB inhibition on hypercholesterolemic rats
NAV da Motta, FCF de Brito - Fundamental & clinical …, 2016 - Wiley Online Library
This work presents a model of rats fed a high‐cholesterol diet, receiving a long‐term oral
administration of cilostazol, a PDE 3‐inhibitor. The aim of this study was to evaluate the …
administration of cilostazol, a PDE 3‐inhibitor. The aim of this study was to evaluate the …
Interaction of platelets with endothelial progenitor cells in the experimental atherosclerosis: Role of transplanted endothelial progenitor cells and platelet …
N Alexandru, E Andrei, E Dragan… - Biology of the …, 2015 - Wiley Online Library
Background information Recent studies suggest that endothelial progenitor cells (EPCs) and
platelets have an important role in repair following vascular injury. Although evidence …
platelets have an important role in repair following vascular injury. Although evidence …
[HTML][HTML] Angiotensin II type 1A receptor signaling facilitates tumor metastasis formation through P-selectin–Mediated interaction of tumor cells with platelets and …
H Amano, Y Ito, F Ogawa, K Eshima, T Suzuki… - The American journal of …, 2013 - Elsevier
Angiotensin II is involved in tumor growth; however, the precise mechanism is not known.
Platelets also contribute to tumor growth, and angiotensin II type 1 receptor (AT1) is …
Platelets also contribute to tumor growth, and angiotensin II type 1 receptor (AT1) is …