Plants employ numerous cell-surface and intracellular immune receptors to perceive a
variety of immunogenic signals associated with pathogen infection and subsequently …

Animal and plant immune systems use intracellular nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) to detect pathogens, resulting in the activation of …

INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

Summary 2′, 3′-cAMP is a positional isomer of the well-established second messenger
3′, 5′-cAMP, but little is known about the biology of this noncanonical cyclic nucleotide …

SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of
nicotinamide adenine dinucleotide in its oxidized form (NAD+) during Wallerian …

INTRODUCTION Plants and animals respond to pathogen invasion through intracellular
nucleotide-binding leucine-rich repeat receptors (NLRs) that directly interact with pathogen …

INTRODUCTION Nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs)
mediate plant immunity by directly or indirectly sensing pathogen effector proteins delivered …

Cyclic adenosine diphosphate (ADP)–ribose (cADPR) isomers are signaling molecules
produced by bacterial and plant Toll/interleukin-1 receptor (TIR) domains via nicotinamide …

Crop breeding aims to balance disease resistance with yield; however, single resistance (R)
genes can lead to resistance breakdown, and R gene pyramiding may affect growth fitness …

Plants have evolved multiple defense strategies to cope with pathogens, among which plant
immune signaling that relies on cell‐surface localized and intracellular receptors takes …