Thousands of unannotated small and alternative open reading frames (smORFs and alt-
ORFs, respectively) have recently been revealed in mammalian genomes. While hundreds …

Cellular proteins are dynamically regulated in response to environmental stimuli.
Conventional proteomics compares the entire proteome in different cellular states to identify …

Proteogenomic identification of translated small open reading frames has revealed
thousands of previously unannotated, largely uncharacterized microproteins, or …

The conserved WD40-repeat protein WDR5 interacts with multiple proteins both inside and
outside the nucleus. However, it is currently unclear whether and how the distribution of …

Ribosomal frameshifting refers to the process that ribosomes slip into+ 1 or− 1 reading
frame, thus produce chimeric trans-frame proteins. In viruses and bacteria, programmed …

Mentha haplocalyx essential oil (MEO) has demonstrated inhibitory effects on Fusarium
oxysporum. Despite its environmentally friendly properties as a natural product, the limited …

Protein coding genes were originally identified with sequence-based definitions that
included a 100-codon cutoff to avoid annotating irrelevant open reading frames. However …

Ribosome biogenesis is the complex and essential process that ultimately leads to the
synthesis of cellular proteins. Understanding each step of this essential process is …

The complexity of the metazoan proteome is significantly increased by the expression of
small proteins (< 100 aa) derived from smORFs within lncRNAs, uORFs, 3′ UTRs and …

RIBO-seq and proteogenomics have revealed that mammalian genomes harbor thousands
of unannotated small and alternative open reading frames (smORFs,< 100 amino acids, and …