The advancement of science and technology has led to the recent development of highly
sensitive pathogen biosensing techniques. The effective treatment of pathogen infections …

Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

Dengue is the most prevalent arboviral disease in humans and a major public health
problem worldwide. Systemic plasma leakage, leading to hypovolemic shock and potentially …

Fucosylation is a biological process broadly observed in vertebrates, invertebrates, plants,
bacteria, and fungi. Fucose moieties on cell-surface glycans are increasingly recognized as …

Unlike their protein “roommates” and their nucleic acid “cousins," carbohydrates remain an
enigmatic arm of biology. The central reason for the difficulty in fully understanding how …

Systemic immunity supports lifelong brain function. Obesity posits a chronic burden on
systemic immunity. Independently, obesity was shown as a risk factor for Alzheimer's …

When refrigerated platelets are rewarmed, they secrete active sialidases, including the
lysosomal sialidase Neu1, and express surface Neu3 that remove sialic acid from platelet …

Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-
containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation …

A bstract This review summarizes the recent research development on vertebrate sialidase
biology. Sialic acid-containing compounds play important roles in many physiological …

Both pathogen-and tissue damage-associated molecular patterns induce inflammation
through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin superfamily …