Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

NKT cells are CD1d-restricted innate-like T cells expressing both T cell receptor and NK cell
markers. The major group of NKT cells in both human and mice is the invariant NKT (iNKT) …

The thymus is critical in establishing and maintaining the appropriate microenvironment for
promoting the development and selection of T cells. The function and structure of the thymus …

Tumor cells utilize co-inhibitory molecules to avoid host immune destruction. Checkpoint
blockade has emerged as a promising approach to treat cancer by restoring T cell effector …

Corneal graft rejection is the major reason for transplant failure. CD25 plays an important
role in the induction of corneal graft rejection by regulating CD4+ T cell function …

Background: It seems that the success of vaccination for cancer immunotherapy such as
Dendritic Cell (DC) based cancer vaccine is hindered through a powerful network of immune …

Natural killer T (NKT) cells are a population of innate-like lymphocytes that express both NK
and T cell markers. Following activation by the recognition of glycolipid antigen presented in …

Tumor diseases are severe problem worldwide with increasing number of patients suffering
from various types of malignancies. Many of approved therapeutics cause serious side …