Simple Summary Breast cancer remains the most common malignancy in women. In this
review, we explore the role of the CXCL12/CXCR4 pathway in breast cancer. We show that …

Accumulating evidence indicates that G protein-coupled receptor kinase 2 (GRK2) is a
versatile protein that acts as a signaling hub by modulating G protein-coupled receptor …

G protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors and their signal transduction is tightly regulated by GPCR kinases (GRKs) and β …

Elevated expression of the chemokine receptors CXCR4 and ACKR3 and of their cognate
ligand CXCL12 is detected in a wide range of tumors and the tumor microenvironment …

G protein‐coupled receptors (GPCRs) represent a large family of transmembrane proteins
that transduce an external stimulus into a variety of cellular responses. They play a critical …

Increasing evidences point to G protein-coupled receptor kinases (GRKs), a subfamily of
protein kinase A/G/C-like kinases, as relevant players in cancer progression, in a cell-type …

CAMKK2 is a serine/threonine kinase and an activator of AMPK whose dysregulation is
linked with multiple diseases. Unfortunately, STO-609, the tool inhibitor commonly used to …

Breast cancer is the most prevalent cancer found in women living in developed countries.
Endocrine therapy is the mainstay of treatment for hormone-responsive breast tumors (about …

Recent evidence suggests that dysregulated eIF3d expression may be critical in various
genetic disorders as well as cancer. In this study, we observed that EIF3d levels increased in …

G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors.
Emerging evidence demonstrates that signaling through GPCRs affects numerous aspects …