Highlights Imaging of the dopamine transporter (DAT)(in particular using 11C-or 18F-PE2I)
most reliably and precisely measures neurodegeneration of the dopaminergic system in …

Gait and balance disorders are common signs in several neurodegenerative diseases such
as Parkinson's disease, atypical parkinsonism, idiopathic normal pressure hydrocephalus …

Parkinson's disease (PD) patients can be classified in tremor-dominant (TD) and postural-
instability-and-gait-disorder (PIGD) motor subtypes. PIGD represents a more aggressive …

Background Few studies interrogated the involvement of cerebellum in modulating gait in
Parkinson's disease (PD) patients with postural instability and gait disorders (PD-PIGD). This …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder that presents a
diagnostic challenge due to symptom overlap with other disorders. Neuromelanin (NM) …

Background Parkinson's disease (PD) is a clinically and neuroanatomically heterogeneous
neurodegenerative disease characterized by different subtypes. To this date, no studies …

Aim To investigate the presence and relationship of temporal speech and gait parameters in
patients with postural instability/gait disorder (PIGD) and tremor‐dominant (TD) motor …

The purpose of this study was to automatically classify different motor subtypes of
Parkinson's disease (PD) on arterial spin labelling magnetic resonance imaging (ASL-MRI) …

Background Parkinson's disease (PD) is highly heterogeneous reflected by different affected
side of body and type of motor symptom. We aim to explore clinical characteristics and …

The neuropathological substrates of Parkinson's disease (PD) patients with motor subtypes
tremor-dominance (TD), non-tremor dominance (nTD), postural instability and gait difficulty …