Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

Publisher Summary This chapter discusses the basis for age-dependent changes in immune
function. Aging converts a fit, mature adult into an increasingly infirm one. The mechanisms …

Alterations in immune function have been commonly reported in elderly persons. We have
examined the effect of age on the responsiveness of natural killer (NK) cells to in vitro …

In this study, the low-molecular-weight (LMW) fucoidan, rich in fucose and sulfate, was
extracted and purified from the edible brown seaweed, Laminaria japonica. In this study, we …

The effect of aging on natural killer cell homeostasis is not well studied in humans or in
animal models. We compared natural killer (NK) cells from young and aged mice to …

The bioaccumulation and immunotoxicity of aluminum (Al) have been previously
documented. Al accumulates in the organs of the organism, including spleen. Spleen is a …

In essence, the immune system is enhanced during moderate and severe exercise, and only
intense long-duration exercise is followed by impairment of the immune system. The latter …

Over the last few years there has been a growing interest in geriatric oncology, mainly
because of the evidence that advanced age is the greatest risk factor for the development of …

The aging process is associated with multiple deficits in pulmonary immune function.
Defense of the airway is impaired in the elderly by decreased mucociliary clearance …

Abstract Concanavalin A (Con A)-induced cytotoxic activity, interferon (IFN) and interleukin-2
(IL-2) levels in cultures of spleen cells from young (2-3 months) and old (22-24 months) …