To combat infection, the fruit fly Drosophila melanogaster relies on multiple innate defense
reactions, many of which are shared with higher organisms. These reactions include the use …

Drosophila mounts a potent host defence when challenged by various microorganisms.
Analysis of this defence by molecular genetics has now provided a global picture of the …

Dysbiosis is a hallmark of inflammatory bowel disease (IBD), but it is unclear which specific
intestinal bacteria predispose to and which protect from IBD and how they are regulated …

This standard-setting textbook has defined the field of immunology since 1984, and is now in
its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage …

Boman HG (Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm,
Sweden). Antibacterial peptides: basic facts and emerging concepts (Review). J Intern Med …

A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode …

Biotic and abiotic factors shape investment in costly defenses. The immune systems of
vertebrates and invertebrates differ in their fitness cost. However, the hygienic behavior of …

All animals, including humans, live in symbiotic association with microorganisms. The
immune system accommodates host colonization by the microbiota, maintains microbiota …

Microbial infection activates two distinct intracellular signalling cascades in the immune-
responsive fat body of Drosophila,. Gram-positive bacteria and fungi predominantly induce …

The immune system provides protection from a wide range of pathogens. One component of
immunity, the phylogenetically ancient innate immune response, fights infections from the …