Potential role of antioxidants as adjunctive therapy in Chagas disease

JP Sánchez-Villamil, PK Bautista-Niño… - Oxidative Medicine …, 2020 - Wiley Online Library
Chagas disease (CD) is one of the most important neglected tropical diseases in the
American continent. Host‐derived nitroxidative stress in response to Trypanosoma cruzi …

The use of antioxidants as potential co-adjuvants to treat chronic chagas disease

E Maldonado, DA Rojas, F Urbina, A Solari - Antioxidants, 2021 - mdpi.com
Chagas disease is a neglected tropical disease caused by the flagellated protozoa
Trypanosome cruzi. This illness affects to almost 8–12 million people worldwide, however, is …

Drug associations as alternative and complementary therapy for neglected tropical diseases

LRM Ferraz, LCPBB Silva, ML de Souza, LP Alves… - Acta Tropica, 2022 - Elsevier
The present paper aims to establish different treatments for neglected tropical disease by a
survey on drug conjugations and possible fixed-dose combinations (FDC) used to obtain …

Ascorbic acid ameriolates liver damage by myeloperoxidase oxidative products in a hamster model of amoebic liver abscess

A Cruz-Baquero, RA Jarillo-Luna… - Frontiers in Cellular …, 2022 - frontiersin.org
Entamoeba histolytica is a protozoan-pathogen-causing amoebic liver abscess (ALA). After
amoeba establishment in the liver, it causes abundant infiltrate of neutrophils. Liver tissue …

[HTML][HTML] Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in β-cyclodextrin complexes and combination with …

J Pozo-Martinez, F Salgado, A Liempi… - Arabian Journal of …, 2022 - Elsevier
American trypanosomiasis or Chagas disease is caused by the protozoan parasite
Trypanosoma cruzi, and is considered a neglected disease, being an important problem for …

The Role of the Oxidative Stress-Inflammation Axis in the COVID-19-Infected Patients with Chagas Disease: A Key Parameter To Be Considered During the Pandemic

D Aydemir, NN Ulusu - Current Clinical Microbiology Reports, 2023 - Springer
Abstract Purpose of Review The global COVID-19 pandemic has become a major public
health problem since December 2019, affecting millions of people, especially individuals …

Mitigation of benznidazole toxicity and oxidative stress following ascorbic acid supplementation in an adult traveller with chronic indeterminate Chagas' disease

S Van Den Broucke, M Van Herreweghe… - Journal of …, 2022 - academic.oup.com
Background Benznidazole is an effective drug in the trypanocidal treatment of acute and
chronic indeterminate Chagas' disease (CD). However, adverse drug reactions (ADR) are …

Evaluación de la actividad tripanocida de la serie 3-aril cumarinas y sus complejos de inclusión con β-ciclodextrina en combinación con benznidazol

JS Pozo Martínez - 2022 - repositorio.uchile.cl
La enfermedad de Chagas o Tripanosomiasis americana es causada por el parásito
protozoario Trypanosoma cruzi afectando aproximadamente a 18 millones de personas en …

Correlation of plasma butyrylcholinesterase concentration with Acethylcholinesterase H353N polymorphism in the inflammatory response of Chagas disease patients

AC Campello, L Zanella, RB Suzuki, MO Tokumo… - Parasitology …, 2020 - Elsevier
Trypanosoma cruzi infection triggers an intense production of pro-inflammatory cytokines
mediated by T helper 1 lymphocytes, inducing the anti-inflammatory reflex of acetylcholine …

Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in bcyclodextrin complexes and combination with benznidazole

JS Pozo Martínez, FJ Salgado Valdés… - 2022 - repositorio.uchile.cl
American trypanosomiasis or Chagas disease is caused by the protozoan parasite
Trypanosoma cruzi, and is considered a neglected disease, being an important problem for …