The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Mass spectrometry approaches to glycomic and glycoproteomic analyses

LR Ruhaak, G Xu, Q Li, E Goonatilleke… - Chemical …, 2018 - ACS Publications
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

A review of bioactive plant polysaccharides: Biological activities, functionalization, and biomedical applications

J Liu, S Willför, C Xu - Bioactive Carbohydrates and Dietary Fibre, 2015 - Elsevier
Natural polysaccharides from different sources have long been studied and widely used in
different areas, such as food and feed, medicine and pharmaceutics, and in papermaking. In …

[HTML][HTML] Advances in dietary polysaccharides as anticancer agents: Structure-activity relationship

N Li, C Wang, MI Georgiev, VK Bajpai, R Tundis… - Trends in Food Science …, 2021 - Elsevier
Background The discovery of nutritious dietary supplements and side effect-free
therapeutics are a priority in the current scenario of increasing cancer cases. Natural …

Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

SA Berkowitz, JR Engen, JR Mazzeo… - Nature Reviews Drug …, 2012 - nature.com
Biologics such as monoclonal antibodies are much more complex than small-molecule
drugs, which raises challenging questions for the development and regulatory evaluation of …

Sources, extraction and biomedical properties of polysaccharides

S Ullah, AA Khalil, F Shaukat, Y Song - Foods, 2019 - mdpi.com
In the recent era, bioactive compounds from plants have received great attention because of
their vital health-related activities, such as antimicrobial activity, antioxidant activity …

Oligosaccharide analysis by mass spectrometry: a review of recent developments

MJ Kailemia, LR Ruhaak, CB Lebrilla… - Analytical …, 2014 - ACS Publications
Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …

High-sensitivity analytical approaches for the structural characterization of glycoproteins

WR Alley Jr, BF Mann, MV Novotny - Chemical reviews, 2013 - ACS Publications
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Annotation and structural analysis of sialylated human milk oligosaccharides

S Wu, R Grimm, JB German… - Journal of proteome …, 2011 - ACS Publications
Sialylated human milk oligosaccharides (SHMOs) are important components of human milk
oligosaccharides. Sialic acids are typically found on the nonreducing end and are known …