The escalating demand for secondary metabolites in international markets poses a severe
threat to many plant species. An unscrupulous collection is also the immediate challenge to …

Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

The seminal discovery of paclitaxel from endophytic fungus Taxomyces andreanae was a
milestone in recognizing the immense potential of endophytic fungi as prolific producers of …

Plant endophytic fungi are an important and novel resource of natural bioactive compounds
with their potential applications in agriculture, medicine and food industry. In the past two …

Cancer is a major killer disease all over the world and more than six million new cases are
reported every year. Nature is an attractive source of new therapeutic compounds, as a …

It is known that plant-based ethnomedicine represented the foundation of modern
pharmacology and that many pharmaceuticals are derived from compounds occurring in …

Camptothecin (CPT), the third largest anticancer drug, is produced mainly by Camptotheca
acuminata and Nothapodytes foetida. CPT itself is the starting material for clinical CPT-type …

This study was conducted to characterize and explore the endophytic fungi of selected
plants from the Western Himalayas for their bioactive potential. A total of 72 strains of …

The current study proposes a bio-directed approach for the formation of titanium oxide and
silver nanoparticles (TiO2 and Ag NPs), using a wild mushroom, Fomitopsis pinicola …

Fungal producing potency of camptothecin (CPT) raise the hope for their usage to be a
platform for industrial production of CPT, nevertheless, attenuation of their productivity of …