[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation

S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Microfluidic tissue engineering and bio‐actuation

M Filippi, T Buchner, O Yasa, S Weirich… - Advanced …, 2022 - Wiley Online Library
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Will microfluidics enable functionally integrated biohybrid robots?

M Filippi, O Yasa, RD Kamm… - Proceedings of the …, 2022 - National Acad Sciences
The next robotics frontier will be led by biohybrids. Capable biohybrid robots require
microfluidics to sustain, improve, and scale the architectural complexity of their core …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

Cancer-on-chip: a 3D model for the study of the tumor microenvironment

E Cauli, MA Polidoro, S Marzorati, C Bernardi… - Journal of Biological …, 2023 - Springer
The approval of anticancer therapeutic strategies is still slowed down by the lack of models
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …

Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment

F Lebre, N Chatterjee, S Costa… - Nanomaterials, 2022 - mdpi.com
The use of nanomaterials has been increasing in recent times, and they are widely used in
industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid …

[HTML][HTML] Thermo-responsive polymers as surface active compounds: A review

N Manfredini, G Gardoni, M Sponchioni… - European Polymer …, 2023 - Elsevier
The great versatility and controllable properties that characterize polymeric materials
allowed their spreading to many different areas. In the last years, this outstanding …

Renal hypoxic reperfusion injury-on-chip model for studying combinational vitamin therapy

AR Chethikkattuveli Salih, A Asif… - ACS Biomaterials …, 2022 - ACS Publications
Renal ischemic-reperfusion injury decreases the chances of long-term kidney graft survival
and may lead to the loss of a transplanted kidney. During organ excision, the cycle of warm …

[HTML][HTML] Human organoids-on-chips for biomedical research and applications

H Wang, X Ning, F Zhao, H Zhao, D Li - Theranostics, 2024 - ncbi.nlm.nih.gov
Human organoids-on-chips (OrgOCs) are the synergism of human organoids (HOs)
technology and microfluidic organs-on-chips (OOCs). OOCs can mimic extrinsic …

Microneedles in advanced microfluidic systems: A systematic review throughout lab and organ-on-a-chip applications

R Maia, V Carvalho, R Lima, G Minas, RO Rodrigues - Pharmaceutics, 2023 - mdpi.com
Microneedles (MNs) have been widely used in biomedical applications for drug delivery and
biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to …