The immunogenetics of tuberculosis (TB) susceptibility
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains the leading cause
of death due to a single bacterial agent, with approximately 10.6 million people developing …
of death due to a single bacterial agent, with approximately 10.6 million people developing …
Mycobacterium tuberculosis complex and human coadaptation: a two-way street complicating host susceptibility to TB
For centuries, the Mycobacterium tuberculosis complex (MTBC) has infected numerous
populations, both human and non-human, causing symptomatic tuberculosis (TB) in some …
populations, both human and non-human, causing symptomatic tuberculosis (TB) in some …
Local ancestry adjusted allelic association analysis robustly captures tuberculosis susceptibility loci
Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease.
The risk of developing active TB is in part determined by host genetic factors. Most genetic …
The risk of developing active TB is in part determined by host genetic factors. Most genetic …
Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture
The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over
100 genes have been studied as candidates for TB susceptibility, and several variants were …
100 genes have been studied as candidates for TB susceptibility, and several variants were …
Association of Single-Nucleotide Polymorphisms in the VDR Gene with Tuberculosis and Infection of Beijing Genotype Mycobacterium tuberculosis
J Yu, M Liu, X Mijiti, H Liu, Q Wang, C Yin… - Infection and Drug …, 2023 - Taylor & Francis
Background The aim of the present study was to investigate the association between vitamin
D receptor (VDR) gene polymorphism and tuberculosis susceptibility, as well as the …
D receptor (VDR) gene polymorphism and tuberculosis susceptibility, as well as the …
Differential NRAMP1gene's D543N genotype frequency: Increased risk of contracting tuberculosis among Venezuelan populations
Z Araujo, M Camargo, DAM Pérez, A Wide… - Human Immunology, 2023 - Elsevier
NRAMP1 and VDR gene polymorphisms have been variably associated with susceptibility
to tuberculosis (TB) amongst populations having different genetic background. NRAMP1 …
to tuberculosis (TB) amongst populations having different genetic background. NRAMP1 …
Association of Mannose-Binding Lectin 2 Gene Polymorphism with Tuberculosis Based on Mycobacterium tuberculosis Lineages
M Liu, Q Wang, H Liu, C Yin, X Mijiti… - Infection and Drug …, 2022 - Taylor & Francis
Purpose Polymorphisms in MBL2 may contribute to the susceptibility to tuberculosis. The
aim of the present study was to determine the associations of the polymorphisms of five loci …
aim of the present study was to determine the associations of the polymorphisms of five loci …
Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from Tanzania
The risk and prognosis of tuberculosis (TB) are affected by both human and bacterial genetic
factors. To identify interacting human and bacterial genetic loci, we leveraged paired human …
factors. To identify interacting human and bacterial genetic loci, we leveraged paired human …
An integrative data-analysis of miRNA-related contributions to the pathophysiology of neuropsychiatric disorders
HJ Prinsloo - 2022 - scholar.sun.ac.za
The detrimental burden of disease brought on by neuropsychiatric disorders (NDs)
continues to hinder societal and personal growth, especially in developing countries where …
continues to hinder societal and personal growth, especially in developing countries where …