Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies
A Zhao, H Zhou, J Yang, M Li, T Niu - Signal Transduction and Targeted …, 2023 - nature.com
Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …
been rising in recent decades. The clinical and molecular features of hematologic …
[HTML][HTML] Genetic Insights Into Leukemia Susceptibility in the Arab Population: A Scoping Review
A Algarni - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
As per the Global Cancer Observatory, the WHO Eastern Mediterranean region (which
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
TERT and TET2 genetic variants affect leukocyte telomere length and clinical outcome in coronary artery disease patients—a possible link to clonal hematopoiesis
TB Opstad, S Solheim, AÅR Pettersen, AA Kalstad… - Biomedicines, 2022 - mdpi.com
Inherited and acquired mutations in hematopoietic stem cells can cause clonal expansion
with increased risk of cardiovascular disease (CVD), a condition known for the clonal …
with increased risk of cardiovascular disease (CVD), a condition known for the clonal …
TET2 rs1548483 SNP Associating with Susceptibility to Molecularly Annotated Polycythemia Vera and Primary Myelofibrosis
DL Lighezan, AS Bojan, M Iancu, RM Pop… - Journal of Personalized …, 2020 - mdpi.com
Background: The complexity of myeloproliferative neoplasms (MPNs) cannot be
characterized by acquired somatic mutations alone. Individual genetic background is …
characterized by acquired somatic mutations alone. Individual genetic background is …
Significance of Somatic Mutation Profiling in CML Beyond BCR-ABL: A Retrospective Study of the Indian Population
P Chaudhary, S Chaudhary, F Patel, S Patel… - Indian Journal of …, 2024 - Springer
Somatic mutation and fusion detection in acute myeloid leukemia to determine disease
subtype and treatment regime is a common practice, but it's not yet employed in chronic …
subtype and treatment regime is a common practice, but it's not yet employed in chronic …
[PDF][PDF] The Association of TET2 Gene Polymorphisms (rs34402524 and rs2454206) and their Haplotypes with Response to Treatment in Chronic Myeloid Leukemia …
NH Ismail, IA Abdulhassan, AHM Al-Faisal - Iraqi Journal of Science, 2024 - iasj.net
Genetic and epigenetic factors affect chronic myeloid leukemia (CML) treatment response.
The aim of the present study was to investigate the association of two TET2single nucleotide …
The aim of the present study was to investigate the association of two TET2single nucleotide …