Near-lifespan longitudinal tracking of brain microvascular morphology, topology, and flow in male mice
In age-related neurodegenerative diseases, pathology often develops slowly across the
lifespan. As one example, in diseases such as Alzheimer's, vascular decline is believed to …
lifespan. As one example, in diseases such as Alzheimer's, vascular decline is believed to …
Neurophotonic tools for microscopic measurements and manipulation: status report
Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …
focused on development of technologies for advancement of neuroscience. For the last …
Review of in silico models of cerebral blood flow in health and pathology
In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
Dynamic Ultrasound Localization Microscopy Without ECG-Gating
Abstract Objective Dynamic Ultrasound Localization Microscopy (DULM) has first been
developed for non-invasive Pulsatility measurements in the rodent brain. DULM relies on the …
developed for non-invasive Pulsatility measurements in the rodent brain. DULM relies on the …
3D transcranial Dynamic Ultrasound Localization Microscopy in the mouse brain using a Row-Column Array
The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed
using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization …
using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization …
Intravital imaging of cardiac tissue utilizing tissue-stabilized heart window chamber in live animal model
For establishing intravital heart microimaging protocol in live mouse models, an optimized
suction-based tissue motion-stabilizing cardiac imaging window chamber system has been …
suction-based tissue motion-stabilizing cardiac imaging window chamber system has been …
Dynamic Imaging using any Ultrasound Localization Microscopy Dataset
N Ghigo, G Ramos-Palacios, C Bourquin… - arXiv preprint arXiv …, 2023 - arxiv.org
Ultrasound Localization Microscopy (ULM) relies on the injection of microbubbles (MBs) to
obtain highly resolved density maps of blood circulation in vivo, with a resolution that can …
obtain highly resolved density maps of blood circulation in vivo, with a resolution that can …
Deep learning and simulation for the estimation of red blood cell flux with optical coherence tomography
We present a deep learning and simulation-based method to measure cortical capillary red
blood cell (RBC) flux using Optical Coherence Tomography (OCT). This method is more …
blood cell (RBC) flux using Optical Coherence Tomography (OCT). This method is more …
Mathematical Models of the Cerebral Microcirculation in Health and Pathophysiology
SJ Payne - … Models, Computational Methods and Data Analysis, 2024 - Springer
The cerebral microcirculation is a highly complex interconnected network of vessels that
cover a wide range of length scales and respond over a wide range of time scales. It plays a …
cover a wide range of length scales and respond over a wide range of time scales. It plays a …
Dissecting the microvascular contributions to diffuse correlation spectroscopy measurements of cerebral hemodynamics using optical coherence tomography …
Significance: Diffuse correlation spectroscopy (DCS) is an emerging noninvasive, diffuse
optical modality that purportedly enables direct measurements of microvasculature blood …
optical modality that purportedly enables direct measurements of microvasculature blood …