Targeting anthracyclines in early breast cancer: new candidate predictive biomarkers emerge
AF Munro, DA Cameron, JMS Bartlett - Oncogene, 2010 - nature.com
The search for a predictive marker of sensitivity to anthracycline-based chemotherapy has
proven challenging. Despite human epidermal growth factor receptor 2 (HER2) being a …
proven challenging. Despite human epidermal growth factor receptor 2 (HER2) being a …
Detecting the formation kinetics of doxorubicin-DNA interstrand cross-link at the single-molecule level and clinically relevant concentrations of doxorubicin
Doxorubicin (DOX) ranks among the most effective anticancer agents. Increasing the
formation of covalent DOX-DNA interstrand cross-links can improve the anticancer activity of …
formation of covalent DOX-DNA interstrand cross-links can improve the anticancer activity of …
Regulation of hepatocyte engraftment and proliferation after cytotoxic drug-induced perturbation of the rat liver
KS Kim, B Joseph, M Inada, S Gupta - Transplantation, 2005 - journals.lww.com
Background. Perturbations in specific liver cell compartments benefit transplanted cell
engraftment and/or proliferation. We analyzed whether cytotoxic drugs interfering with the …
engraftment and/or proliferation. We analyzed whether cytotoxic drugs interfering with the …
Barminomycin, a model for the development of new anthracyclines
K Kimura, DMS Spencer, R Bilardi… - Anti-Cancer Agents …, 2010 - ingentaconnect.com
Barminomycin is a member of the anthracycline class of anticancer agents and was
originally discovered as a pink/red complex with DNA and RNA and named SN-07. The …
originally discovered as a pink/red complex with DNA and RNA and named SN-07. The …