Cardiac metabolic remodelling in chronic kidney disease

N Patel, MM Yaqoob, D Aksentijevic - Nature Reviews Nephrology, 2022 - nature.com
Chronic kidney disease (CKD) affects millions of people globally and, for most patients, the
risk of developing cardiovascular disease is higher than that of progression to kidney failure …

Na+/Ca2+ exchange and Na+/K+‐ATPase in the heart

MJ Shattock, M Ottolia, DM Bers… - The Journal of …, 2015 - Wiley Online Library
This paper is the third in a series of reviews published in this issue resulting from the
University of California Davis Cardiovascular Symposium 2014: Systems approach to …

Uremic cardiomyopathy: an underdiagnosed disease

E Alhaj, N Alhaj, I Rahman, TO Niazi… - Congestive heart …, 2013 - Wiley Online Library
Uremic cardiomyopathy is responsible for high morbidity and mortality rates among patients
with chronic kidney disease (CKD) or end‐stage renal disease (ESRD); however, the early …

Mechanisms and modulation of oxidative/nitrative stress in type 4 cardio-renal syndrome and renal sarcopenia

M Sárközy, ZZA Kovács, MG Kovács, R Gáspár… - Frontiers in …, 2018 - frontiersin.org
Chronic kidney disease (CKD) is a public health problem and a recognized risk factor for
cardiovascular diseases (CVD). CKD could amplify the progression of chronic heart failure …

Clinical potential of targeting fibroblast growth Factor‐23 and αKlotho in the treatment of uremic cardiomyopathy

JP Law, AM Price, L Pickup… - Journal of the …, 2020 - Am Heart Assoc
Chronic kidney disease is highly prevalent, affecting 10% to 15% of the adult population
worldwide and is associated with increased cardiovascular morbidity and mortality. As …

Uremic cardiomyopathy and insulin resistance: a critical role for akt?

D Semple, K Smith, S Bhandari… - Journal of the American …, 2011 - journals.lww.com
Uremic cardiomyopathy is a classic complication of chronic renal failure whose cause is
unclear and treatment remains disappointing. Insulin resistance is an independent predictor …

Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy

ZZA Kovács, G Szűcs, M Freiwan, MG Kovács… - Scientific Reports, 2021 - nature.com
Uremic cardiomyopathy is characterized by diastolic dysfunction (DD), left ventricular
hypertrophy (LVH), and fibrosis. Angiotensin-II plays a major role in the development of …

Association of kidney function and hemoglobin with left ventricular morphology among African Americans: the Atherosclerosis Risk in Communities (ARIC) study

BC Astor, DK Arnett, A Brown, J Coresh - American journal of kidney …, 2004 - Elsevier
Background: Left ventricular (LV) hypertrophy (LVH) is present in more than 70% of patients
with kidney failure. Hypertension and anemia, 2 strong risk factors for LVH, are common in …

Chronic kidney disease induces left ventricular overexpression of the pro-hypertrophic microRNA-212

M Sárközy, R Gáspár, Á Zvara, A Siska, B Kővári… - Scientific Reports, 2019 - nature.com
Chronic kidney disease (CKD) is a public health problem that increases the risk of
cardiovascular morbidity and mortality. Heart failure with preserved ejection fraction (HFpEF) …

Reversible cardiomyopathies

H Patel, R Madanieh, CE Kosmas… - Clinical Medicine …, 2015 - journals.sagepub.com
Cardiomyopathies (CMs) have many etiological factors that can result in severe structural
and functional dysregulation. Fortunately, there are several potentially reversible CMs that …