2023 Guideline for the management of patients with aneurysmal subarachnoid hemorrhage: a guideline from the American Heart Association/American Stroke …

BL Hoh, NU Ko, S Amin-Hanjani, SHY Chou… - Stroke, 2023 - Am Heart Assoc
Aim: The “2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid
Hemorrhage” replaces the 2012 “Guidelines for the Management of Aneurysmal …

Inflammation and oxidative stress: potential targets for improving prognosis after subarachnoid hemorrhage

F Wu, Z Liu, G Li, L Zhou, K Huang, Z Wu… - Frontiers in cellular …, 2021 - frontiersin.org
Subarachnoid hemorrhage (SAH) has a high mortality rate and causes long-term disability
in many patients, often associated with cognitive impairment. However, the pathogenesis of …

Puerarin attenuates oxidative stress and ferroptosis via AMPK/PGC1α/Nrf2 pathway after subarachnoid hemorrhage in rats

Y Huang, H Wu, Y Hu, C Zhou, J Wu, Y Wu, H Wang… - Antioxidants, 2022 - mdpi.com
Puerarin was shown to exert anti-oxidative and anti-ferroptosis effects in multiple diseases.
The goal of this study was to explore the neuroprotective effect of puerarin on early brain …

Activation of SIRT1 alleviates ferroptosis in the early brain injury after subarachnoid hemorrhage

B Yuan, XD Zhao, JD Shen, SJ Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Ferroptosis is a regulated cell death that characterizes the lethal lipid peroxidation and iron
overload, which may contribute to early brain injury (EBI) pathogenesis after subarachnoid …

Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury

Y Chen, I Galea, RL Macdonald, GKC Wong… - …, 2022 - thelancet.com
Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …

Isoliquiritigenin mitigates oxidative damage after subarachnoid hemorrhage in vivo and in vitro by regulating Nrf2-dependent Signaling Pathway via Targeting of …

JQ Liu, XT Zhao, FY Qin, JW Zhou, F Ding, G Zhou… - Phytomedicine, 2022 - Elsevier
Background Oxidative stress is a crucial factor leading to subarachnoid hemorrhage (SAH)-
induced early brain injury (EBI). Isoliquiritigenin has been verified as a powerful anti-oxidant …

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway

Z Liu, Z Zhou, P Ai, C Zhang, J Chen… - Frontiers in …, 2022 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a severe type of stroke featuring exceptionally high rate
of morbidity and mortality due to the lack of effective management. Ferroptosis can be …

[HTML][HTML] New mechanisms and targets of subarachnoid hemorrhage: a focus on mitochondria

Z Zhang, A Zhang, Y Liu, X Hu, Y Fang… - Current …, 2022 - ncbi.nlm.nih.gov
Spontaneous subarachnoid hemorrhage (SAH) accounts for 5-10% of all strokes and is a
subtype of hemorrhagic stroke that places a heavy burden on health care. Despite great …

The novel function of bexarotene for neurological diseases

Y Liu, P Wang, G Jin, P Shi, Y Zhao, J Guo, Y Yin… - Ageing Research …, 2023 - Elsevier
Bexarotene, a retinoid X receptor (RXR) agonist, is approved by FDA to treat cutaneous T-
cell lymphoma. However, it has also demonstrated promising therapeutic potential for …

[HTML][HTML] Deep learning-assisted identification and quantification of aneurysmal subarachnoid hemorrhage in non-contrast CT scans: development and external …

P Hu, H Zhou, T Yan, H Miu, F Xiao, X Zhu, L Shu… - Neuroimage, 2023 - Elsevier
Accurate stroke assessment and consequent favorable clinical outcomes rely on the early
identification and quantification of aneurysmal subarachnoid hemorrhage (aSAH) in non …