The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Glioblastoma multiforme (GBM) is abnormal cell proliferation of glial cells. GBM is the grade
IV glioma brain cancer which is life-threatening to many individuals affected by this cancer …

Glioblastoma multiforme (GBM) is an aggressive brain tumor with high mortality rates. Due to
its invasiveness, heterogeneity, and incomplete resection, the treatment is very challenging …

Even though the last decade has seen a surge in the identification of molecular targets and
targeted therapies in pediatric brain tumors, the blood brain barrier (BBB) remains a …

At the moment, anaplastic changes within the brain are challenging due to the complexity of
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …

Abstract Temozolomide (TMZ), an imidazotetrazine, is a second-generation DNA alkylating
agent used as a first-line treatment of glioblastoma multiforme (GBM). It was approved by …

Targeted delivery of neurological therapeutic to the brain has been attracting more and more
attention to the treatment of central nervous system (CNS) diseases. Nonetheless, the main …

Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …

Abstract Alzheimer's disease (AD), which is a prevailing type of dementia, presents a
significant global health concern. The current therapies do not meet clinical expectations …

Momordica. charantia has antioxidant and neuroprotective effects, but its anti-glioma
capacity remains unclear. Plant-derived nanovesicles have shown therapeutic potential in …