Three-dimensional in vitro culture models in oncology research

C Jubelin, J Muñoz-Garcia, L Griscom, D Cochonneau… - Cell & Bioscience, 2022 - Springer
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra-
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …

Functional supramolecular polymers for biomedical applications

R Dong, Y Zhou, X Huang, X Zhu, Y Lu… - Advanced …, 2015 - Wiley Online Library
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …

[HTML][HTML] Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery

R Mo, Z Gu - Materials Today, 2016 - Elsevier
Cancer-associated stimuli-responsive nanosystems have been increasingly considered for
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …

Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: promises, progress and prospects

C Deng, Y Jiang, R Cheng, F Meng, Z Zhong - Nano today, 2012 - Elsevier
Biodegradable polymeric micelles have emerged as one of the most promising platforms for
targeted and controlled anticancer drug delivery due to their excellent biocompatibility …

Lotus effect in wetting and self-cleaning

M Zhang, S Feng, L Wang, Y Zheng - Biotribology, 2016 - Elsevier
Self-cleaning surfaces based on lotus effect with a very high static water contact angle
greater than 160° and a lower roll-off angle have been successfully studied by researchers …

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

JA Finbloom, F Sousa, MM Stevens… - Advanced drug delivery …, 2020 - Elsevier
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery

T Thambi, VG Deepagan, HY Yoon, HS Han, SH Kim… - Biomaterials, 2014 - Elsevier
Hypoxia is a condition found in various intractable diseases. Here, we report self-assembled
nanoparticles which can selectively release the hydrophobic agents under hypoxic …

Bioapplications of hyperbranched polymers

D Wang, T Zhao, X Zhu, D Yan, W Wang - Chemical Society Reviews, 2015 - pubs.rsc.org
Hyperbranched polymers (HBPs), an important subclass of dendritic macromolecules, are
highly branched, three-dimensional globular nanopolymeric architectures. Attractive …

Synthesis and applications of stimuli-responsive hyperbranched polymers

D Wang, Y Jin, X Zhu, D Yan - Progress in Polymer Science, 2017 - Elsevier
Benefiting from their responsiveness and adaptability, the stimuli-responsive polymers have
been widely investigated and exploited in the various fields, such as environmental …

[HTML][HTML] Intracellular drug release nanosystems

F Meng, R Cheng, C Deng, Z Zhong - Materials today, 2012 - Elsevier
In order to elicit therapeutic effects, many drugs including small molecule anticancer drugs,
proteins, siRNA, and DNA have to be delivered and released into the specific cellular …