Three-dimensional in vitro culture models in oncology research
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra-
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
Functional supramolecular polymers for biomedical applications
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …
display specific structural and physicochemical properties, but also have the ability to …
[HTML][HTML] Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery
Cancer-associated stimuli-responsive nanosystems have been increasingly considered for
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …
Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: promises, progress and prospects
Biodegradable polymeric micelles have emerged as one of the most promising platforms for
targeted and controlled anticancer drug delivery due to their excellent biocompatibility …
targeted and controlled anticancer drug delivery due to their excellent biocompatibility …
Lotus effect in wetting and self-cleaning
M Zhang, S Feng, L Wang, Y Zheng - Biotribology, 2016 - Elsevier
Self-cleaning surfaces based on lotus effect with a very high static water contact angle
greater than 160° and a lower roll-off angle have been successfully studied by researchers …
greater than 160° and a lower roll-off angle have been successfully studied by researchers …
Engineering the drug carrier biointerface to overcome biological barriers to drug delivery
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …
Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery
Hypoxia is a condition found in various intractable diseases. Here, we report self-assembled
nanoparticles which can selectively release the hydrophobic agents under hypoxic …
nanoparticles which can selectively release the hydrophobic agents under hypoxic …
Bioapplications of hyperbranched polymers
Hyperbranched polymers (HBPs), an important subclass of dendritic macromolecules, are
highly branched, three-dimensional globular nanopolymeric architectures. Attractive …
highly branched, three-dimensional globular nanopolymeric architectures. Attractive …
Synthesis and applications of stimuli-responsive hyperbranched polymers
Benefiting from their responsiveness and adaptability, the stimuli-responsive polymers have
been widely investigated and exploited in the various fields, such as environmental …
been widely investigated and exploited in the various fields, such as environmental …
[HTML][HTML] Intracellular drug release nanosystems
In order to elicit therapeutic effects, many drugs including small molecule anticancer drugs,
proteins, siRNA, and DNA have to be delivered and released into the specific cellular …
proteins, siRNA, and DNA have to be delivered and released into the specific cellular …