Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering

C Chen, X Bai, Y Ding, IS Lee - Biomaterials research, 2019 - spj.science.org
Recently, electrical stimulation as a physical stimulus draws lots of attention. It shows great
potential in disease treatment, wound healing, and mechanism study because of significant …

Unraveling the mechanistic effects of electric field stimulation towards directing stem cell fate and function: A tissue engineering perspective

G Thrivikraman, SK Boda, B Basu - Biomaterials, 2018 - Elsevier
Electric field (EF) stimulation can play a vital role in eliciting appropriate stem cell response.
Such an approach is recently being established to guide stem cell differentiation through …

Electrical stimulation in bone tissue engineering treatments

L Leppik, KMC Oliveira, MB Bhavsar… - European Journal of …, 2020 - Springer
Electrical stimulation (EStim) has been shown to promote bone healing and regeneration
both in animal experiments and clinical treatments. Therefore, incorporating EStim into …

Electric field-responsive nanoparticles and electric fields: physical, chemical, biological mechanisms and therapeutic prospects

J Kolosnjaj-Tabi, L Gibot, I Fourquaux, M Golzio… - Advanced drug delivery …, 2019 - Elsevier
Electric fields are among physical stimuli that have revolutionized therapy. Occurring
endogenously or exogenously, the electric field can be used as a trigger for controlled drug …

Accelerating bioelectric functional development of neural stem cells by graphene coupling: implications for neural interfacing with conductive materials

R Guo, S Zhang, M Xiao, F Qian, Z He, D Li, X Zhang… - Biomaterials, 2016 - Elsevier
In order to govern cell-specific behaviors in tissue engineering for neural repair and
regeneration, a better understanding of material-cell interactions, especially the bioelectric …

Electric field stimulation for tissue engineering applications

CNM Ryan, MN Doulgkeroglou, DI Zeugolis - BMC Biomedical …, 2021 - Springer
Electric fields are involved in numerous physiological processes, including directional
embryonic development and wound healing following injury. To study these processes in …

Biophysical stimuli as the fourth pillar of bone tissue engineering

Z Hao, Z Xu, X Wang, Y Wang, H Li, T Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
The repair of critical bone defects remains challenging worldwide. Three canonical pillars
(biomaterial scaffolds, bioactive molecules, and stem cells) of bone tissue engineering have …

Electrical stimulation in cartilage tissue engineering

R Vaiciuleviciute, I Uzieliene, P Bernotas, V Novickij… - Bioengineering, 2023 - mdpi.com
Electrical stimulation (ES) has been frequently used in different biomedical applications both
in vitro and in vivo. Numerous studies have demonstrated positive effects of ES on cellular …

Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds

S Song, D Amores, C Chen, K McConnell, B Oh… - Scientific Reports, 2019 - nature.com
Human induced pluripotent stem cell-derived neural progenitor cells (hNPCs) are a
promising cell source for stem cell transplantation to treat neurological diseases such as …

Effects of electric fields on human mesenchymal stem cell behaviour and morphology using a novel multichannel device

TA Banks, PSB Luckman, JE Frith… - Integrative …, 2015 - academic.oup.com
The intrinsic piezoelectric nature of collagenous-rich tissues, such as bone and cartilage,
can result in the production of small, endogenous electric fields (EFs) during applied …