Particulate matter air pollutants and cardiovascular disease: Strategies for intervention

A Aryal, AC Harmon, TR Dugas - Pharmacology & therapeutics, 2021 - Elsevier
Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …

[HTML][HTML] Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors

MTB Jimenez, K Frenis, O Hahad, S Steven… - Free Radical Biology …, 2022 - Elsevier
Environmental risk factors, including noise, air pollution, chemical agents, ultraviolet
radiation (UVR) and mental stress have a considerable impact on human health. Oxidative …

ABCB1 and ABCG2 regulation at the blood-brain barrier: potential new targets to improve brain drug delivery

JA Schulz, AMS Hartz, B Bauer - Pharmacological Reviews, 2023 - ASPET
The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery
of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have been largely …

[HTML][HTML] Electronic cigarette aerosol modulates the oral microbiome and increases risk of infection

S Pushalkar, B Paul, Q Li, J Yang, R Vasconcelos… - Iscience, 2020 - cell.com
The trend of e-cigarette use among teens is ever increasing. Here we show the dysbiotic
oral microbial ecology in e-cigarette users influencing the local host immune environment …

Conductive polymer‐based bioelectronic platforms toward sustainable and biointegrated devices: a journey from skin to brain across human body interfaces

O Bettucci, GM Matrone… - Advanced Materials …, 2022 - Wiley Online Library
Over the last few years, organic bioelectronics has experienced an exponential growth with
applications encompassing platforms for tissue engineering, drug delivery systems …

[HTML][HTML] Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity

J Ebersole, V Samburova, Y Son… - Tobacco induced …, 2020 - ncbi.nlm.nih.gov
Use of electronic nicotine delivery systems (ENDS), such as electronic cigarettes (e-cigs), is
increasing across the US population and is particularly troubling due to their adoption by …

Neurotoxicity of e-cigarettes

JA Ruszkiewicz, Z Zhang, FM Gonçalves… - Food and Chemical …, 2020 - Elsevier
It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

[HTML][HTML] Cigarette smoke-induced reactive oxygen species formation: a concise review

YS Seo, JM Park, JH Kim, MY Lee - Antioxidants, 2023 - mdpi.com
Smoking is recognized as a significant risk factor for numerous disorders, including
cardiovascular diseases, respiratory conditions, and various forms of cancer. While the exact …

[HTML][HTML] Traumatic brain injury and blood–brain barrier (BBB): underlying pathophysiological mechanisms and the influence of cigarette smoking as a premorbid …

F Sivandzade, F Alqahtani, L Cucullo - International journal of molecular …, 2020 - mdpi.com
Traumatic brain injury (TBI) is among the most pressing global health issues and prevalent
causes of cerebrovascular and neurological disorders all over the world. In addition to the …

[HTML][HTML] Cerebrovascular and neurological disorders: protective role of NRF2

F Sivandzade, A Bhalerao, L Cucullo - International journal of molecular …, 2019 - mdpi.com
Cellular defense mechanisms, intracellular signaling, and physiological functions are
regulated by electrophiles and reactive oxygen species (ROS). Recent works strongly …