Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems

VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022 - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Recent advances in kaolinite nanoclay as drug carrier for bioapplications: a review

Q Wu, J Liao, H Yang - Advanced Science, 2023 - Wiley Online Library
Advanced functional two‐dimensional (2D) nanomaterials offer unique advantages in drug
delivery systems for disease treatment. Kaolinite (Kaol), a nanoclay mineral, is a natural 2D …

Hydrogel-based ocular drug delivery systems for hydrophobic drugs

C Torres-Luna, X Fan, R Domszy, N Hu… - European Journal of …, 2020 - Elsevier
Conventional ophthalmic dosage forms such as eye drops pose a significant challenge
because physiological barriers and clearance mechanisms limit ocular bioavailability …

Recent advances in the design of topical ophthalmic delivery systems in the treatment of ocular surface inflammation and their biopharmaceutical evaluation

R Mazet, JBG Yaméogo, D Wouessidjewe… - Pharmaceutics, 2020 - mdpi.com
Ocular inflammation is one of the most common symptom of eye disorders and diseases.
The therapeutic management of this inflammation must be rapid and effective in order to …

Chitosan derivatives with mucoadhesive and antimicrobial properties for simultaneous nanoencapsulation and extended ocular release formulations of …

A Karava, M Lazaridou, S Nanaki, G Michailidou… - Pharmaceutics, 2020 - mdpi.com
The aim of this work was to evaluate the effectiveness of neat chitosan (CS) and its
derivatives with 2-acrylamido-2-methyl-1-propanesulfonic acid (AAMPS) and [2 …

Chondroitin sulfate and L-Cysteine conjugate modified cationic nanostructured lipid carriers: Pre-corneal retention, permeability, and related studies for dry eye …

R Zhu, W Chen, D Gu, T Wang, J Li, H Pan - International Journal of …, 2023 - Elsevier
In this study, a novel bioadhesive material, a conjugate of chondroitin sulfate and L-cysteine
(CS-Cys), was synthesized and modified on the surface of the cationic nanostructured lipid …

Design and optimization of gatifloxacin loaded polyvinyl alcohol nanofiber for the treatment of dry eye infection: In vitro and in vivo evaluation

DK Sahu, D Pradhan, J Halder, P Biswasroy… - Journal of Drug Delivery …, 2022 - Elsevier
According to a clinical report, nearly 50% of dry eye patients have an elevated risk of ocular
infections and inflammations. Nanofiber could serve as a potential vehicle for treating …

Bentonite clay incorporated topical film formulation for delivery of trimetazidine: Control of ocular pressure and in vitro-in vivo correlation

R Swain, S Nandi, RN Sahoo, SS Swain… - Journal of Drug Delivery …, 2022 - Elsevier
Bentonite clay based film formulation has been prepared for topical delivery of trimetazidine
(TZ) for the control of ocular pressure. Trimetazidine ophthalmic film formulation has been …

PLA–PCL–PEG–PCL–PLA based micelles for improving the ocular permeability of dexamethasone: development, characterization, and in vitro evaluation

M Alami-Milani, P Zakeri-Milani… - Pharmaceutical …, 2020 - Taylor & Francis
The aim of the present research was to investigate the feasibility of developing polylactide–
polycaprolactone–polyethylene glycol–polycaprolactone–polylactide (PLA–PCL–PEG–PCL …

Kaolinite nanomaterials: preparation, properties and functional applications

H Cheng, Y Zhou, Q Liu - Nanomaterials from Clay Minerals, 2019 - Elsevier
As an important industrial raw material, kaolinite has a wide variety of applications in many
fields. It can be exfoliated into few-layered nanosheets with exquisite physicochemical …