Background Antibiotic resistance (ABR) is one of the biggest threats to global health.
Infections by ESKAPE (Enterococcus, S. aureus, K. pneumoniae, A. baumannii, P …

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Abstract The World Health Organization (WHO) reports that the emergence of multidrug-
resistant and the slow advent of novel and more potent antitumor and antimicrobial …

Blood culture remains the best approach to identify the incriminating microorganisms when
a bloodstream infection is suspected, and to guarantee that the antimicrobial treatment is …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Microbial infections remain the principal cause for high morbidity and mortality rates. While
approximately 1400 human pathogens have been recognized, the majority of healthcare …

The polymyxins, colistin (also known as polymyxin E) and polymyxin B, have a unique and
interesting history. Originally introduced in the 1950s for the treatment of infections due to …

Viruses are obligate intracellular pathogens that require the protein synthesis machinery of
the host cells to replicate. These microorganisms have evolved mechanisms to avoid …

ABSTRACT Relebactam (formerly MK-7655) is an inhibitor of class A and C β-lactamases,
including Klebsiella pneumoniae carbapenemase (KPC), and is currently in clinical …

Antimicrobial resistance against colistin has emerged worldwide and is threatening the
efficacy of colistin treatment of multi-resistant Gram-negative bacteria. In this study, PCRs …